Results 11 to 20 of about 171,876 (350)
Linking Cellular and Mechanical Processes in Articular Cartilage Lesion Formation: A Mathematical Model [PDF]
, 2016 A severe application of stress on articular cartilage can initiate a cascade of biochemical reactions that can lead to the development of osteoarthritis.
Ayati, Bruce P. +4 more
core +7 more sources
Applied Sciences, 2022 The aim of the study was to assess the effects of therapeutic ultrasound (US) on oxidative stress (OS)-induced changes in cultured human chondrocytes (HCH). For this, monolayer HCH were randomized in three groups: a control group (CG), a group exposed to
Rodica Ana Ungur +14 more
doaj +1 more source
Detection and characterization of Sp1 binding activity in human chondrocytes and its alterations during chondrocyte dedifferentiation. [PDF]
, 1997 We have detected DNA binding activity for a synthetic oligonucleotide containing an Sp1 consensus sequence in nuclear extracts from human chondrocytes. Changes in the levels of Sp1 oligonucleotide binding activity were examined in nuclear extracts from ...
Dharmavaram, Rita M. +3 more
core +2 more sources
In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
, 2010 We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada +9 more
core +1 more source
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
core +5 more sources
Chinese Medical Journal, 2021 . Background. Previous studies have reported that mitochondrial dysfunction participates in the pathological process of osteoarthritis (OA). However, studies that improve mitochondrial function are rare in OA. Mitochondrial transfer from mesenchymal stem
Rui Wang +5 more
doaj +1 more source
Comparison of Apoptosis and Autophagy in Human Chondrocytes Induced by the T-2 and HT-2 Toxins
Toxins, 2019 In this report, we have investigated the apoptosis and autophagy of chondrocytes induced by the T-2 and HT-2 toxins. The viability of chondrocytes was measured by the MTT assay.
Fang-Fang Yu +4 more
doaj +1 more source
npj Regenerative Medicine, 2021 Osteoarthritis (OA) causes serious changes in the metabolic and signaling pathways of chondrocytes, including the mitogen-activated protein kinase (MAPK) pathway.
Sunghyun Park +6 more
doaj +1 more source
A homeostatic function of CXCR2 signalling in articular cartilage [PDF]
, 2014 Funding This work was funded by Arthritis Research UK (grants 17859, 17971, 19654), INNOCHEM EU FP6 (grant LSHB-CT-2005-51867), MRC (MR/K013076/1) and the William Harvey Research FoundationPeer reviewedPublisher ...
Aberdeen +17 more
core +3 more sources
CCL2 induces articular chondrocyte MMP expression through ERK and p38 signaling pathways
Osteoarthritis and Cartilage Open, 2021 Objective: In previous studies, we determined an association between increased serum and articular cartilage levels of CCL2 with osteoarthritis (OA) progression, cartilage damage and increased MMP13 in cartilage.
Helen Willcockson +4 more
doaj +1 more source