Results 51 to 60 of about 48,511 (262)

Dietary supplementation with glycosaminoglycans reduces locomotor problems in broiler chickens

Poultry Science, 2020
This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet on the performance and incidence of locomotor problems in broiler chickens. A completely randomized design was carried out in
Julyana M.S. Martins, Lindolfo D. dos Santos Neto, Raiana A. Noleto-Mendonça, Genilson B. de Carvalho, Sarah Sgavioli, Fabyola Barros de Carvalho, Nadja S.M. Leandro, Marcos B. Café   +7 more
doaj  

Anticonvulsive Effects of Chondroitin Sulfate on Pilocarpine and Pentylenetetrazole Induced Epileptogenesis in Mice

Molecules, 2021
Chondroitin sulfate is a proteoglycan component of the extracellular matrix (ECM) that supports neuronal and non-neuronal cell activity, provides a negative domain to the extracellular matrix, regulates the intracellular positive ion concentration, and ...
Shareen Singh, Thakur Gurjeet Singh, Manjinder Singh, Agnieszka Najda, Renata Nurzyńska-Wierdak, Rafa Almeer, Mohamed Kamel, Mohamed M. Abdel-Daim   +7 more
doaj   +1 more source

Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand

Advanced Science, EarlyView.
Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li, Hwan D. Kim, Allen C. Luo, Liyan Gong, Yonglin Zhu, Chin Nien Lee, Xuechong Hong, Christopher L. Sudduth, Michal Ad, Young‐Hyeon An, Mihn Jeong Park, Do‐Gyoon Kim, Arin K. Greene, Bonnie L. Padwa, Nathaniel S. Hwang, Ruei‐Zeng Lin, Juan M. Melero‐Martin   +16 more
wiley   +1 more source

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

Advanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi, Claudia Corbo, Julia Enterria‐Rosales, John Otto Martinez, Silvia Minardi, Laura Pandolfi, Xing Wang, Ennio Tasciotti, Kavindra V. Singh, Cesar A. Arias, Bruna Corradetti   +10 more
wiley   +1 more source

LITERATURE REVIEW ON GLUCOSAMINE AND CHONDROITIN IN OSTEOARTHRITIS TREATMENT

Tạp chí Khoa học
Osteoarthritis is a chronic disease primarily characterized by articular cartilage damage. In Vietnam, osteoarthritis accounts for a high percentage of musculoskeletal conditions, especially affecting the knee joints.
Dang Thi Soa*, Vu Thi Thuy, Nguyen Duc Trung, Bien Thi Thuc Uyen, Le Thi Hai Yen, Tran Trung Hieu, Tran Thao Linh
doaj   +1 more source

Neuroactive Chondroitin Sulfate Glycomimetics [PDF]

Journal of the American Chemical Society, 2008
We report the generation of chondroitin sulfate (CS) glycomimetics with tunable chemical and biological properties. Our approach greatly simplifies the synthesis of complex glycosaminoglycans, providing synthetically accessible, bioactive structures of programmable sulfation sequence.
Rawat, Manish, Gama, Cristal I., Matson, John B., Hsieh-Wilson, Linda C.   +3 more
openaire   +5 more sources

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

Structum therapy of patients with rheumatoid arthri-tis

Терапевтический архив, 2004
Aim. To study efficacy of the chondroprotector chondroitin sulphate (structum, Pier Fabr Medicament Production, France) in patients with rheumatoid arthritis (RA) and secondary osteoarthrosis of the knee joints. Material and methods. 15 women with a long
Ye I Shmidt, I V Belozerova, F M Akhmedzhanov, D G Soldatov   +3 more
doaj  

Antigenicity of Chondroitin Sulfate.

Experimental Biology and Medicine, 1957
SummaryChondroitin sulfate extracted from human costal cartilage was prepared in 3 different ways for inoculation into rabbits, (1) a 1% solution, (2) a 1% solution incubated with heat-killed, group A, type 3, hemolytic streptococcus, and (3) a 1% solution incubated with heat-killed Staphylococcus aureus. These 3 preparations were injected into rabbits
Robert W. Quinn, Rose E. Cerroni
openaire   +3 more sources

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source