Results 21 to 30 of about 15,622 (209)
Differential expression of proteoglycans in tissue remodeling and lymphangiogenesis after experimental renal transplantation in rats. [PDF]
PLoS ONE, 2010 BACKGROUND: Chronic transplant dysfunction explains the majority of late renal allograft loss and is accompanied by extensive tissue remodeling leading to transplant vasculopathy, glomerulosclerosis and interstitial fibrosis. Matrix proteoglycans mediate
Heleen Rienstra +6 more
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The effect of using chondroitin sulfate in osteoarthritis of the knee
Journal of Education, Health and Sport, 2023 Introduction: Osteoarthritis is the most common disease of the musculoskeletal system. It develops in the regulation of the quality and quantity of articular cartilage, which cushions the joint and improves the sliding of the articular surfaces ...
Ziemowit Żaba +9 more
doaj +1 more source
Statistical method for analysis of interactions between chosen protein and chondroitin sulfate in an aqueous environment [PDF]
, 2022 We present the statistical method to study the interaction between a chosen protein and another molecule (e.g., both being components of lubricin found in synovial fluid) in a water environment. The research is performed on the example of univariate time series of chosen features of the dynamics of mucin, which interact with chondroitin sulfate (4 and ...
arxiv +1 more source
CD44 binds a chondroitin sulfate proteoglycan, aggrecan [PDF]
International Immunology, 2001 Here we report that CD44 binds a chondroitin sulfate (CS) proteoglycan, aggrecan, a major component of cartilage. Soluble CD44-IgG and CD44(+) cells bound to aggrecan from rat chondrosarcoma and bovine cartilage, immobilized on microtiter plates. In both cases, binding was blocked by a neutralizing anti-CD44 mAb or by the pretreatment of aggrecan with ...
Hiroto Kawashima +6 more
openaire +3 more sources
Proteoglycans and neuronal migration in the cerebral cortex during development and disease
Frontiers in Neuroscience, 2015 Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many proteins including growth factors, chemokines, axon guidance molecules,
Nobuaki eMaeda
doaj +1 more source
Journal of Neuroinflammation, 2012 Background Chondroitin sulfate proteoglycans are major inhibitory molecules for neural plasticity under both physiological and pathological conditions. The chondroitin sulfate degrading enzyme chondroitinase ABC promotes functional recovery after spinal ...
Tauchi Ryoji +8 more
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Regulation of Synthesis of Chondroitin Sulfate Proteoglycan [PDF]
Upsala Journal of Medical Sciences, 1977 (1977). Regulation of Synthesis of Chondroitin Sulfate Proteoglycan. Upsala Journal of Medical Sciences: Vol. 82, No. 2, pp. 76-77.
openaire +3 more sources
Antioxidant, antiinflammatory and neuroprotective actions of chondroitin sulfate and proteoglycans [PDF]
Osteoarthritis and Cartilage, 2010 The antiinflammatory and antiapoptotic effects of chondroitin sulfate (CS) are being used to treat osteoarthritis. Recent evidence has revealed that those peripheral effects of CS may also have therapeutic interest in diseases of the central nervous system (CNS). We review here such evidence.
Manuela G. López +4 more
openaire +2 more sources
Galactosaminoglycan Function and Oligosaccharide Structure Determination
The Scientific World Journal, 2007 This review will discuss the importance of sequencing long chondroitin sulfate and dermatan sulfate chains specifically derived from decorin. Decorin is a member of the small leucine-rich repeat proteoglycans and ubiquitously expressed primarily in the ...
Daniela G. Seidler +2 more
doaj +1 more source
Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells
Scientific Reports, 2022 Proteoglycans are proteins that are modified with glycosaminoglycan chains. Chondroitin sulfate proteoglycans (CSPGs) are currently being exploited as targets for drug-delivery in various cancer indications, however basic knowledge on how CSPGs are ...
Chris Kedong Wang +16 more
doaj +1 more source