Results 21 to 30 of about 30,507 (276)
Chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS) are covalently attached to specific core proteins to form proteoglycans in their biosynthetic pathways.
Shuji Mizumoto, Shuhei Yamada
doaj +1 more source
The spondylodysplastic type of Ehlers–Danlos syndrome (spEDS) is caused by genetic defects in the B4GALT7 or B3GALT6 genes both deranging the biosynthesis of the glycosaminoglycan linkage region of chondroitin/dermatan sulfate and heparan sulfate ...
Mahnaz Nikpour +7 more
doaj +1 more source
: This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet of broilers on the expression of matrix metallopeptidase 9 (MMP-9) and metallopeptidase inhibitor 2 (TIMP-2) genes, the ...
Julyana M.S. Martins +8 more
doaj +1 more source
Differential expression of proteoglycans in tissue remodeling and lymphangiogenesis after experimental renal transplantation in rats. [PDF]
BACKGROUND: Chronic transplant dysfunction explains the majority of late renal allograft loss and is accompanied by extensive tissue remodeling leading to transplant vasculopathy, glomerulosclerosis and interstitial fibrosis. Matrix proteoglycans mediate
Heleen Rienstra +6 more
doaj +1 more source
The effect of using chondroitin sulfate in osteoarthritis of the knee
Introduction: Osteoarthritis is the most common disease of the musculoskeletal system. It develops in the regulation of the quality and quantity of articular cartilage, which cushions the joint and improves the sliding of the articular surfaces ...
Ziemowit Żaba +9 more
doaj +1 more source
CD44 binds a chondroitin sulfate proteoglycan, aggrecan [PDF]
Here we report that CD44 binds a chondroitin sulfate (CS) proteoglycan, aggrecan, a major component of cartilage. Soluble CD44-IgG and CD44(+) cells bound to aggrecan from rat chondrosarcoma and bovine cartilage, immobilized on microtiter plates. In both cases, binding was blocked by a neutralizing anti-CD44 mAb or by the pretreatment of aggrecan with ...
T, Fujimoto +6 more
openaire +2 more sources
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. [PDF]
Vertebrates produce multiple chondroitin sulfate proteoglycans that play important roles in development and tissue mechanics. In the nematode Caenorhabditis elegans, the chondroitin chains lack sulfate but nevertheless play essential roles in embryonic ...
Bishop, Joseph R +4 more
core +2 more sources
大腸菌を用いたフォスファカン(コンドロイチン硫酸プロテオグリカン)の融合コア蛋白の発現条件の検討 [PDF]
Optimal conditions for expressing a specific region of core protein of phosphacan, a chondroitin sulfate proteoglycan known as receptor type protein tyrosine phosphatase, as fusion protein with glutathione S-transferase (GST) in E.coli were examined. DNA
Ito, Sekiko, Okamoto, Motoi
core +1 more source
Glycosaminoglycans in the human cornea: age-related changes [PDF]
AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia +6 more
core +2 more sources
Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination [PDF]
AbstractObjective:Failure of remyelination is a critical impediment to recovery in multiple sclerosis (MS). Chondroitin sulfate proteoglycans (CSPGs) have been reported to accumulate in MS lesions, and we thus examined the functional roles of CSPGs on oligodendrocyte precursor cells (OPCs), oligodendrocytes, and remyelination.Methods:We evaluated the ...
Lorraine Lau +8 more
openalex +3 more sources

