Results 1 to 10 of about 392,110 (289)
Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts [PDF]
Oncoprotein 18 (Op18) is a microtubule-destabilizing protein that is negatively regulated by phosphorylation. To evaluate the role of the three Op18 phosphorylation sites in Xenopus (Ser 16, 25, and 39), we added wild-type Op18, a nonphosphorylatable ...
Andersen+67 more
core +4 more sources
EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences. [PDF]
The availability of genome-wide epigenomic datasets enables in-depth studies of epigenetic modifications and their relationships with chromatin structures and gene expression.
Ge, Xinzhou+5 more
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Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms [PDF]
Alteration of chromatin structure by chromatin modifying and remodelling activities is a key stage in the regulation of many nuclear processes. These activities are frequently interlinked, and many chromatin remodelling enzymes contain motifs that ...
Ferreira, Helder+2 more
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In living cells, DNA is packaged along with protein and RNA into chromatin. Chemical modifications to nucleotides and histone proteins are added, removed and recognized by multi-functional molecular complexes. Here I define a new computational model, in which chromatin modifications are information units that can be written onto a one-dimensional ...
openaire +5 more sources
Chromatin and Epigenetics [PDF]
Wrapping DNA around protein beads, to form so-called nucleosomes, is an ingenious invention of nature allowing the condensation of an enormous amount of genomic information into a tiny package.
Doris Wagner, Anna Amtmann, Hong Ma
openaire +3 more sources
Influence of M-phase chromatin on the anisotropy of microtubule asters [PDF]
In many eukaryotic cells going through M-phase, a bipolar spindle is formed by microtubules nucleated from centrosomes. These microtubules, in addition to being "captured" by kinetochores, may be stabilized by chromatin in two different ways: short-range
Dogterom, M.+3 more
core +2 more sources
Chromatin Preparation and Chromatin Immuno-precipitation from Drosophila Embryos
This protocol provides specific details on how to perform Chromatin immunoprecipitation (ChIP) from Drosophila embryos. ChIP allows the matching of proteins or histone modifications to specific genomic regions.
Iovino, N., Latrielle, D., Löser, E.
core +1 more source
The Structure of Chromatin [PDF]
The DNA in chromatin of isolated thymus nuclei, and in two different preparations of deoxyribonucleoprotein extracted from chromatin, has been digested with DNase. By variation of the time of reaction and the concentration of enzyme, and by comparison of the action of the enzyme on (protein-free) DNA with its action on DNA complexed with protein in ...
openaire +3 more sources
Minor Loops in Major Folds: Enhancer-Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease. [PDF]
The organization and folding of chromatin within the nucleus can determine the outcome of gene expression. Recent technological advancements have enabled us to study chromatin interactions in a genome-wide manner at high resolution.
Ahituv, Nadav, Matharu, Navneet
core +1 more source
Chromatin Structure in the Cellular Slime Mold Dictyostelium discoideum [PDF]
The structure of Dictyostelium discoideum chromatin has been studied by the following techniques: electron microscopy, staphylococcal nuclease digestion, acrylamide gel electrophoresis, sucrose gradient centrifugation, and melting.
Bakke, Antony C.+2 more
core