Results 11 to 20 of about 83,148 (303)
The quantitative architecture of centromeric chromatin [PDF]
eLife, 2014 The centromere, responsible for chromosome segregation during mitosis, is epigenetically defined by CENP-A containing chromatin. The amount of centromeric CENP-A has direct implications for both the architecture and epigenetic inheritance of centromeres.
Dani L Bodor +9 more
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An Isochore Framework Underlies Chromatin Architecture. [PDF]
PLoS ONE, 2017 A recent investigation showed the existence of correlations between the architectural features of mammalian interphase chromosomes and the compositional properties of isochores.
Kamel Jabbari, Giorgio Bernardi
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Manipulating chromatin architecture in C. elegans
Epigenetics & Chromatin, 2022 Background Nucleosome-mediated chromatin compaction has a direct effect on the accessibility of trans-acting activators and repressors to DNA targets and serves as a primary regulatory agent of genetic expression. Understanding the nature and dynamics of
John L. Carter +3 more
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Genetic Architecture of Transcription and Chromatin Regulation [PDF]
Genomics & Informatics, 2015 DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic signatures. In particular, chromatin opening is tightly coupled with gene transcription.
Kwoneel Kim +3 more
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Editorial: Probing the Chromatin Architecture [PDF]
Frontiers in Cell and Developmental Biology, 2021 Francesca Palombo +4 more
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Architecture of the chromatin in the interphase Nucleus [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Introduction I. 3D organization of the chromatin in the interphase nucleus 1. Relationship of the chromatin with the nucleus structures 2. Notion of chromosomal territories 3. Topography of the territories 4. Interface between neighbor territories 5. Organization model of the chromatin in the interphase nucleus II. Relative evolution of the territories
Dupont, JM
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Chromatin Organisation and Genome Architecture [PDF]
Dynamic yet functionally stable organization of cellular processes is a crucial feature of biological systems, allowing them to respond to external stimuli and survive. The eukaryotic nucleus represents a complex subcellular organelle where DNA and RNA metabolism occurs through spatio-temporally organized processes that change dynamically during the ...
Pabba, Maruthi Kumar
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Architectural RNA in chromatin organization [PDF]
Biochemical Society Transactions, 2020 RNA plays a well-established architectural role in the formation of membraneless interchromatin nuclear bodies. However, a less well-known role of RNA is in organizing chromatin, whereby specific RNAs have been found to recruit chromatin modifier proteins.
Jitendra Thakur, Steven Henikoff
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The Dynamic Chromatin Architecture of the Regenerating Liver [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2019 ABSTRACT Background & Aims The adult liver is the main detoxification organ and is routinely exposed to environmental insults but retains the ability to restore its mass and function upon tissue damage.
Wang, Amber W. +5 more
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Chromatin Architecture Reconstruction [PDF]
Biophysical Journal, 2012 Three-dimensional genomic architecture is increasingly being found to play an important role in the regulation of gene expression through direct physical interactions of distant genomic sites. Conformation Capture Techniques (CCTs) attempt to resolve the conformation of a genetic sequence or entire genome by measuring mean interaction frequencies ...
Diesinger, Philipp M. +4 more
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