An Isochore Framework Underlies Chromatin Architecture. [PDF]
PLoS ONE, 2017 A recent investigation showed the existence of correlations between the architectural features of mammalian interphase chromosomes and the compositional properties of isochores.
Kamel Jabbari, Giorgio Bernardi
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Manipulating chromatin architecture in C. elegans
Epigenetics & Chromatin, 2022 Background Nucleosome-mediated chromatin compaction has a direct effect on the accessibility of trans-acting activators and repressors to DNA targets and serves as a primary regulatory agent of genetic expression. Understanding the nature and dynamics of
John L. Carter +3 more
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The quantitative architecture of centromeric chromatin [PDF]
eLife, 2014 The centromere, responsible for chromosome segregation during mitosis, is epigenetically defined by CENP-A containing chromatin. The amount of centromeric CENP-A has direct implications for both the architecture and epigenetic inheritance of centromeres.
Dani L Bodor +9 more
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Editorial: Probing the Chromatin Architecture [PDF]
Frontiers in Cell and Developmental Biology, 2021 Francesca Palombo +4 more
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Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis [PDF]
Nature CommunicationsThe three-dimensional folding of chromosomes is essential for nuclear functions such as DNA replication and gene regulation. The emergence of chromatin architecture is thus an important process during embryogenesis.
Jonas Coßmann +9 more
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Lnc-ing Trained Immunity to Chromatin Architecture [PDF]
Frontiers in Cell and Developmental Biology, 2019 Human innate immune cells exposed to certain infections or stimuli develop enhanced immune responses upon re-infection with a different second stimulus, a process termed trained immunity.
Stephanie Fanucchi +2 more
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Live-cell visualisation of chromatin for the study of radiation-induced chromosome aberrations [PDF]
, 2011 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.Chromosomes can be visualised during the metaphase stage of the cell cycle however, there are various limitations associated with the visualisation of ...
Malis, Georgios
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Acetic acid produced by Staphylococcus epidermidis remodels chromatin architecture and suppresses gene expression in Malassezia restricta [PDF]
mBioThe skin microbiome is composed of diverse microbial communities that engage in interkingdom interactions, influencing host physiology and microbial balance. Although Malassezia restricta and Staphylococcus epidermidis are codominant members of the human
Jae Min Lee +7 more
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Architectural RNA in chromatin organization [PDF]
Biochemical Society Transactions, 2020 RNA plays a well-established architectural role in the formation of membraneless interchromatin nuclear bodies. However, a less well-known role of RNA is in organizing chromatin, whereby specific RNAs have been found to recruit chromatin modifier proteins.
Jitendra Thakur, Steven Henikoff
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The Dynamic Chromatin Architecture of the Regenerating Liver [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2019 ABSTRACT Background & Aims The adult liver is the main detoxification organ and is routinely exposed to environmental insults but retains the ability to restore its mass and function upon tissue damage.
Wang, Amber W. +5 more
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