Results 11 to 20 of about 2,271,159 (299)

Architecture of the chromatin in the interphase Nucleus [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Introduction I. 3D organization of the chromatin in the interphase nucleus 1. Relationship of the chromatin with the nucleus structures 2. Notion of chromosomal territories 3. Topography of the territories 4. Interface between neighbor territories 5. Organization model of the chromatin in the interphase nucleus II. Relative evolution of the territories
Dupont, JM
openaire   +4 more sources

An Isochore Framework Underlies Chromatin Architecture. [PDF]

PLoS ONE, 2017
A recent investigation showed the existence of correlations between the architectural features of mammalian interphase chromosomes and the compositional properties of isochores.
Kamel Jabbari, Giorgio Bernardi
doaj   +4 more sources

Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis

Nature Communications
The three-dimensional folding of chromosomes is essential for nuclear functions such as DNA replication and gene regulation. The emergence of chromatin architecture is thus an important process during embryogenesis.
Jonas Coßmann, Pavel I. Kos, Vassiliki Varamogianni-Mamatsi, Devin S. Assenheimer, Tobias A. Bischof, Timo Kuhn, Thomas Vomhof, Argyris Papantonis, Luca Giorgetti, J. Christof M. Gebhardt   +9 more
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Manipulating chromatin architecture in C. elegans

Epigenetics & Chromatin, 2022
Background Nucleosome-mediated chromatin compaction has a direct effect on the accessibility of trans-acting activators and repressors to DNA targets and serves as a primary regulatory agent of genetic expression. Understanding the nature and dynamics of
John L. Carter, Colton E. Kempton, Emily D. S. Hales, Steven M. Johnson   +3 more
doaj   +3 more sources

The quantitative architecture of centromeric chromatin [PDF]

eLife, 2014
The centromere, responsible for chromosome segregation during mitosis, is epigenetically defined by CENP-A containing chromatin. The amount of centromeric CENP-A has direct implications for both the architecture and epigenetic inheritance of centromeres.
Dani L Bodor, João F Mata, Mikhail Sergeev, Ana Filipa David, Kevan J Salimian, Tanya Panchenko, Don W Cleveland, Ben E Black, Jagesh V Shah, Lars ET Jansen   +9 more
doaj   +6 more sources

Editorial: Probing the Chromatin Architecture [PDF]

Frontiers in Cell and Developmental Biology, 2021
Francesca Palombo, Stefano Pagliara, Ankur Singh, Ankur Singh, Richard Chahwan   +4 more
doaj   +3 more sources

Lnc-ing Trained Immunity to Chromatin Architecture [PDF]

Frontiers in Cell and Developmental Biology, 2019
Human innate immune cells exposed to certain infections or stimuli develop enhanced immune responses upon re-infection with a different second stimulus, a process termed trained immunity.
Stephanie Fanucchi, Stephanie Fanucchi, Musa M. Mhlanga   +2 more
doaj   +3 more sources

Chromatin Organisation and Genome Architecture

Dynamic yet functionally stable organization of cellular processes is a crucial feature of biological systems, allowing them to respond to external stimuli and survive. The eukaryotic nucleus represents a complex subcellular organelle where DNA and RNA metabolism occurs through spatio-temporally organized processes that change dynamically during the ...
Pabba, Maruthi Kumar
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Architectural RNA in chromatin organization [PDF]

Biochemical Society Transactions, 2020
RNA plays a well-established architectural role in the formation of membraneless interchromatin nuclear bodies. However, a less well-known role of RNA is in organizing chromatin, whereby specific RNAs have been found to recruit chromatin modifier proteins.
Jitendra Thakur, Steven Henikoff
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Live-cell visualisation of chromatin for the study of radiation-induced chromosome aberrations [PDF]

, 2011
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.Chromosomes can be visualised during the metaphase stage of the cell cycle however, there are various limitations associated with the visualisation of ...
Malis, Georgios
core   +6 more sources