Results 31 to 40 of about 329,145 (275)

Chromatin looping is needed for iPSC induction [PDF]

Cell Cycle, 2013
Terminally differentiated somatic cells can be reset to pluripotent capability either by ectopic expression of defined factors to form so-called “induced pluripotent stem cells” (iPSCs)1 or by empl...
Hu, Ji-Fan, Hoffman, Andrew R
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A supervised learning framework for chromatin loop detection in genome-wide contact maps

Nature Communications, 2020
Predicting chromatin loops from genome-wide interaction matrices such as Hi-C data provides insight into gene regulation events. Here, the authors present Peakachu, a Random Forest classification framework that predicts chromatin loops from genome-wide ...
Tarik J. Salameh, Xiaotao Wang, Fan Song, Bo Zhang, Sage M. Wright, Chachrit Khunsriraksakul, Yijun Ruan, Feng Yue   +7 more
doaj   +1 more source

Open chromatin interaction maps reveal functional regulatory elements and chromatin architecture variations during wheat evolution

Genome Biology, 2022
Background Bread wheat (Triticum aestivum) is an allohexaploid that is generated by two subsequent allopolyploidization events. The large genome size (16 Gb) and polyploid complexity impede our understanding of how regulatory elements and their ...
Jingya Yuan, Haojie Sun, Yijin Wang, Lulu Li, Shiting Chen, Wu Jiao, Guanghong Jia, Longfei Wang, Junrong Mao, Zhongfu Ni, Xiue Wang, Qingxin Song   +11 more
doaj   +1 more source

The attachments of chromatin loops to the nucleoskeleton

Cell Biology International Reports, 1992
It is widely assumed by cell biologists that chromatin is looped by attachment to some nuclear skeleton. 'Structural' attachments might be mediated through specific sequences; these would be attached in most cells in an organism, underlying the basic structure of the mitotic chromosome and persisting throughout interphase.
Jackson, D, Dolle, A, Robertson, G, Cook, P   +3 more
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Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv [PDF]

, 2010
Copyright: © 2010 Pink et al.Higher order chromatin folding is critical to a number of developmental processes, including the regulation of gene expression.
Christopher H Eskiw, Christopher H. Eskiw, David R F Carter, Eskiw, CH, Daniel P Caley, Pink Ryan C., David R. F. Carter, Caley, DP, Ryan C Pink, Caley, D, Carter, D, Daniel P. Caley, Eskiw Christopher H., Caley Daniel P., Pink, R, Ryan C. Pink, Eskiw, C, Carter David R. F.   +17 more
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Pharmacologic control of chromatin looping [PDF]

Blood, 2015
In this issue of Blood , [Krivega et al][1] establish a new method to reactivate fetal hemoglobin (HbF) production in adult human erythroid cells through pharmacologic manipulation of chromatin looping at the β-globin locus.[1][2] ![Figure][3] Different approaches to reactivate fetal γ-
openaire   +2 more sources

SMARANDACHE LOOPS [PDF]

, 2002
The theory of loops (groups without associativity), though researched by several mathematicians has not found a sound expression, for books, be it research level or otherwise, solely dealing with the properties of loops are absent.
VASANTHA, KANDASAMY
core   +1 more source

Chromatin Conformation in Development and Disease

Frontiers in Cell and Developmental Biology, 2021
Chromatin domains and loops are important elements of chromatin structure and dynamics, but much remains to be learned about their exact biological role and nature.
Ilias Boltsis, Frank Grosveld, Guillaume Giraud, Guillaume Giraud, Petros Kolovos   +4 more
doaj   +1 more source

Comparison of chromatin loops among cell types.

, 2022
(a) Distance distribution of DLoopCaller identified chromatin loops from Hi-C contact maps by using CTCF ChIA-PET data after training on GM12878, H1-ESC, and K562 (replicate1) separately.
Qinhu Zhang (12219347), Kyungsook Han (19287), Ying He (125930), Zhen Cui (2966148), De-Shuang Huang (396909), Siguo Wang (12219350), Zhenghao Guo (7238795)   +6 more
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Non-specific interactions are sufficient to explain the position of heterochromatic chromocenters and nucleoli in interphase nuclei [PDF]

, 2009
The organization of the eukaryote nucleus into functional compartments arises by self-organization both through specific protein–protein and protein–DNA interactions and non-specific interactions that lead to entropic effects, such as e.g.
Nooijer, S., de, Bisseling, T., Wellink, J., de Nooijer, S., Mulder, B.   +4 more
core   +1 more source