Results 51 to 60 of about 329,145 (275)

Super-resolution visualization and modeling of human chromosomal regions reveals cohesin-dependent loop structures

open access: yesGenome Biology, 2021
Background The 3D organization of the chromatin fiber in cell nuclei plays a key role in the regulation of gene expression. Genome-wide techniques to score DNA-DNA contacts, such as Hi-C, reveal the partitioning of chromosomes into epigenetically defined
Xian Hao   +6 more
doaj   +1 more source

An holomorphic study of the Smarandache concept in loops [PDF]

open access: yes, 2006
If two loops are isomorphic, then it is shown that their holomorphs are also isomorphic.
Gbolahan, Temitope
core   +1 more source

CTCF mediates the cell-type specific spatial organization of the Kcnq5 locus and the local gene regulation. [PDF]

open access: yesPLoS ONE, 2012
Chromatin loops play important roles in the dynamic spatial organization of genes in the nucleus. Growing evidence has revealed that the multivalent functional zinc finger protein CCCTC-binding factor (CTCF) is a master regulator of genome spatial ...
Licheng Ren   +5 more
doaj   +1 more source

A Pair of Smarandachely Isotopic Quasigroups and Loops of the Same Variety [PDF]

open access: yes, 2008
The isotopic invariance or universality of types and varieties of quasigroups and loops described by one or more equivalent identities has been of interest to researchers in loop theory in the recent past.
Gbolahan, Temitope   +1 more
core   +1 more source

R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.

open access: yesPLoS Genetics, 2014
Friedreich ataxia (FRDA) and Fragile X syndrome (FXS) are among 40 diseases associated with expansion of repeated sequences (TREDs). Although their molecular pathology is not well understood, formation of repressive chromatin and unusual DNA structures ...
Matthias Groh   +3 more
doaj   +1 more source

Chromatin: A Connection Between Loops and Barriers? [PDF]

open access: yesCurrent Biology, 2002
A genetic screen for proteins that can block the spread of silenced heterochromatin has identified components of the nuclear pores with potential barrier activity. These results suggest that formation of loops of chromatin anchored to the pore could be one mechanism of barrier function.
openaire   +2 more sources

Pericentric Chromatin Is Organized into an Intramolecular Loop in Mitosis [PDF]

open access: yesCurrent Biology, 2008
Cohesin proteins link sister chromatids and provide the basis for tension between bi-oriented sister chomatids in mitosis. Cohesin is concentrated at the centromere region of the chromosome despite the fact that sister centromeres can be separated by 800nm in vivo. The function of cohesin at sites of separated DNA is unknown.
Yeh, Elaine   +7 more
openaire   +2 more sources

Chromatin loops of eight Gossypium species.

open access: yes, 2021
Chromatin loops of eight Gossypium ...
Jianying Li (9426689)
core   +1 more source

LASCA: loop and significant contact annotation pipeline

open access: yesScientific Reports, 2021
Chromatin loops represent one of the major levels of hierarchical folding of the genome. Although the situation is evolving, current methods have various difficulties with the accurate mapping of loops even in mammalian Hi-C data, and most of them fail ...
Artem V. Luzhin   +6 more
doaj   +1 more source

Multi-scale phase separation by explosive percolation with single-chromatin loop resolution

open access: yesComputational and Structural Biotechnology Journal, 2022
The 2 m-long human DNA is tightly intertwined into the cell nucleus of the size of 10 μm. The DNA packing is explained by folding of chromatin fiber.
Kaustav Sengupta   +8 more
doaj   +1 more source

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