Results 51 to 60 of about 303,776 (147)

LASCA: loop and significant contact annotation pipeline

open access: yesScientific Reports, 2021
Chromatin loops represent one of the major levels of hierarchical folding of the genome. Although the situation is evolving, current methods have various difficulties with the accurate mapping of loops even in mammalian Hi-C data, and most of them fail ...
Artem V. Luzhin   +6 more
doaj   +1 more source

Multi-scale phase separation by explosive percolation with single-chromatin loop resolution

open access: yesComputational and Structural Biotechnology Journal, 2022
The 2 m-long human DNA is tightly intertwined into the cell nucleus of the size of 10 μm. The DNA packing is explained by folding of chromatin fiber.
Kaustav Sengupta   +8 more
doaj   +1 more source

Chromatin: A Connection Between Loops and Barriers? [PDF]

open access: yesCurrent Biology, 2002
A genetic screen for proteins that can block the spread of silenced heterochromatin has identified components of the nuclear pores with potential barrier activity. These results suggest that formation of loops of chromatin anchored to the pore could be one mechanism of barrier function.
openaire   +2 more sources

CRISPR-Mediated Reorganization of Chromatin Loop Structure [PDF]

open access: yesJournal of Visualized Experiments, 2018
Recent studies have clearly shown that long-range, three-dimensional chromatin looping interactions play a significant role in the regulation of gene expression, but whether looping is responsible for or a result of alterations in gene expression is still unknown.
Morgan, Stefanie L.   +11 more
openaire   +2 more sources

Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map

open access: yes, 2017
Significance Chromatin loops, detected by chemical cross-linking and DNA sequencing, are frequently bounded by the polycomb repressive complex 1 in Drosophila .
Kyle P. Eagen   +2 more
core   +1 more source

A Pair of Smarandachely Isotopic Quasigroups and Loops of the Same Variety [PDF]

open access: yes, 2008
The isotopic invariance or universality of types and varieties of quasigroups and loops described by one or more equivalent identities has been of interest to researchers in loop theory in the recent past.
Gbolahan, Temitope
core   +1 more source

CGLoop: a neural network framework for chromatin loop prediction

open access: yesBMC Genomics
Background Chromosomes of species exhibit a variety of high-dimensional organizational features, and chromatin loops, which are fundamental structures in the three-dimensional (3D) structure of the genome. Chromatin loops are visible speckled patterns on
Junfeng Wang   +6 more
doaj   +1 more source

SMARANDACHE LOOPS [PDF]

open access: yes, 2002
The theory of loops (groups without associativity), though researched by several mathematicians has not found a sound expression, for books, be it research level or otherwise, solely dealing with the properties of loops are absent.
VASANTHA, KANDASAMY
core   +1 more source

R loops regulate promoter-proximal chromatin architecture and cellular differentiation

open access: yes, 2015
Numerous chromatin-remodeling factors are regulated by interactions with RNA, although the contexts and functions of RNA binding are poorly understood.
Chen, Hsiuyi V.   +4 more
core   +1 more source

SMARANDACHE LOOPS [PDF]

open access: yes, 2010
In this paper we study the notion of Smarandache loops. We obtain some interesting results about them. The notion of Smarandache semigroups homomorphism is studied as well in this paper.
Vasantha Kandasamy, W. B.
core   +1 more source

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