Results 71 to 80 of about 303,776 (147)

The anatomy of transcriptionally active chromatin loops in Drosophila primary spermatocytes using super-resolution microscopy: Supplementary data.

open access: yes, 2023
The anatomy of transcriptionally active chromatin loops in Drosophila primary spermatocytes using super-resolution microscopy: Supplementary data.
Leila Muresan (167566)   +5 more
core   +1 more source

An holomorphic study of the Smarandache concept in loops [PDF]

open access: yes, 2006
If two loops are isomorphic, then it is shown that their holomorphs are also isomorphic.
Gbolahan, Temitope
core   +1 more source

The co-enrichment of transcription factors on identified chromatin loops in H1-ESC with CTCF ChIA-PET training model.

open access: yes, 2022
The co-enrichment of transcription factors on identified chromatin loops in H1-ESC with CTCF ChIA-PET training model.
Qinhu Zhang (12219347)   +6 more
core   +1 more source

SATB1-mediated functional packaging of chromatin into loops [PDF]

open access: yesMethods, 2012
Mammalian genomes are organized into multiple layers of higher-order chromatin structure, and in this organization chromatin looping is a striking and crucial feature that brings together distal genomic loci into close spatial proximity. Such three-dimensional organization of chromatin has been suggested to be functionally important in gene regulation.
Kohwi-Shigematsu, Terumi   +6 more
openaire   +4 more sources

Repulsive forces between looping chromosomes induce entropy-driven segregation. [PDF]

open access: yesPLoS ONE, 2011
One striking feature of chromatin organization is that chromosomes are compartmentalized into distinct territories during interphase, the degree of intermingling being much smaller than expected for linear chains.
Manfred Bohn, Dieter W Heermann
doaj   +1 more source

ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin [PDF]

open access: yes, 2016
A novel chromosome simulator recapitulates the position and dynamics of centromeric chromatin in a model composed of cross-linked intramolecular loops.
Bloom, Kerry   +8 more
core   +1 more source

Hierarchical cooperation of transcription factors from integration analysis of DNA sequences, ChIP-Seq and ChIA-PET data

open access: yesBMC Genomics, 2019
Background Chromosomal architecture, which is constituted by chromatin loops, plays an important role in cellular functions. Gene expression and cell identity can be regulated by the chromatin loop, which is formed by proximal or distal enhancers and ...
Ruimin Wang   +6 more
doaj   +1 more source

Boosting the detection of enhancer-promoter loops via normalization methods for chromatin interaction data

open access: yesNature Communications
Accurate detection of enhancer-promoter loops from genome-wide chromatin interaction data is critical for understanding gene regulation. Standard normalization methods, such as matrix balancing approaches, are widely used to correct biases in chromatin ...
Xiaotao Wang   +5 more
doaj   +1 more source

A Bioconductor/R Workflow for the Detection and Visualization of Differential Chromatin Loops [version 1; peer review: 2 approved]

open access: yesF1000Research
Background Chromatin loops play a critical role in gene regulation by connecting regulatory loci and gene promoters. The identification of changes in chromatin looping between cell types or biological conditions is an important task for understanding ...
Eric Davis   +4 more
doaj   +1 more source

Role of Chromatin Looping Factors in Leukemia

open access: yesAnnual Review of Pathology: Mechanisms of Disease
Genomic organization requires an intricate balance between the compact storage of genetic material and the ability to finely tune gene regulation. Chromatin looping achieves this balance by organizing concordantly regulated groups of genes and their regulatory elements into loops while also condensing DNA to fit into the small volume of a nucleus.
Shira G, Glushakow-Smith   +1 more
openaire   +2 more sources

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