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Spatiotemporal occupancy patterns of chronic wasting disease [PDF]

open access: yesFrontiers in Veterinary Science
IntroductionChronic wasting disease (CWD) among cervids in Kansas has seen a consistent rise over the years, both in terms of the number of infections and its geographical spread.
Amy J. Davis   +6 more
doaj   +4 more sources

Chronic Wasting Disease: State of the Science [PDF]

open access: yesPathogens
Chronic wasting disease (CWD) is a prion disease affecting cervid species, both free-ranging and captive populations. As the geographic range continues to expand and disease prevalence continues to increase, CWD will have an impact on cervid populations,
Jason C. Bartz   +11 more
doaj   +4 more sources

Prospective fecal microbiomic biomarkers for chronic wasting disease [PDF]

open access: yesMicrobiology Spectrum, 2023
Chronic wasting disease (CWD) is a naturally occurring prion disease in cervids that has been rapidly proliferating in the United States. Here, we investigated a potential link between CWD infection and gut microbiome by analyzing 50 fecal samples ...
Adam Didier   +12 more
doaj   +4 more sources

Susceptibility of Beavers to Chronic Wasting Disease

open access: yesBiology, 2022
Chronic wasting disease (CWD) is a contagious, fatal, neurodegenerative prion disease of cervids. The expanding geographical range and rising prevalence of CWD are increasing the risk of pathogen transfer and spillover of CWD to non-cervid sympatric ...
Allen Herbst   +8 more
doaj   +5 more sources

Monitoring of chronic wasting disease (CWD) (IV)

open access: yesEFSA Journal, 2023
The European Commission requested an analysis of the Chronic Wasting Disease (CWD) monitoring programme in Norway, Sweden, Finland, Iceland, Estonia, Latvia, Lithuania and Poland (9 January 2017–28 February 2022). Thirteen cases were detected in reindeer,
EFSA Panel on Biological Hazards (BIOHAZ)   +24 more
doaj   +7 more sources

Genetic Variation and Strain Dynamics in Chronic Wasting Disease [PDF]

open access: yesViruses
Chronic wasting disease (CWD) is a prion disease of cervids marked by growing strain diversity and variation in host susceptibility. Central to this complexity are prion protein gene (Prnp) polymorphisms, which can modulate pathogenesis by altering the ...
Irina Zemlyankina   +5 more
doaj   +2 more sources

Chronic wasting disease as a model for human prion therapy [PDF]

open access: yesPrion
Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are fatal neurodegenerative disorders that result from abnormally folded prion proteins. These disorders can be sporadic, acquired, or genetic.
Michael Bordonaro
doaj   +2 more sources

Scrapie versus Chronic Wasting Disease in White-Tailed Deer [PDF]

open access: yesEmerging Infectious Diseases
White-tailed deer are susceptible to scrapie (WTD scrapie) after oronasal inoculation with the classical scrapie agent from sheep. Deer affected by WTD scrapie are difficult to differentiate from deer infected with chronic wasting disease (CWD).
Zoe J. Lambert   +4 more
doaj   +2 more sources

Association Study of the M132L Single Nucleotide Polymorphism With Susceptibility to Chronic Wasting Disease in Korean Elk: A Meta-Analysis

open access: yesFrontiers in Veterinary Science, 2022
Chronic wasting disease (CWD) is a deleterious brain proteinopathy caused by a pathogenic form of prion protein (PrPSc), which is converted from a benign form of prion protein (PrPC) encoded by the prion protein gene (PRNP).
In-Soon Roh   +11 more
doaj   +1 more source

Mouse models of chronic wasting disease: A review

open access: yesFrontiers in Virology, 2023
Animal models are essential tools for investigating and understanding complex prion diseases like chronic wasting disease (CWD), an infectious prion disease of cervids (elk, deer, moose, and reindeer). Over the past several decades, numerous mouse models
Makayla Cook   +2 more
doaj   +1 more source

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