When the sun never sets: diverse activity rhythms under continuous daylight in free-living arctic-breeding birds [PDF]
, 2013 Circadian clocks are centrally involved in the regulation of daily behavioural and physiological processes. These clocks are synchronized to the 24-hour day by external cues (Zeitgeber), the most important of which is the light-dark cycle.
Helm, B. +5 more
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The Circadian Clock, the Immune System, and Viral Infections: The Intricate Relationship Between Biological Time and Host-Virus Interaction [PDF]
, 2020 Living beings spend their lives and carry out their daily activities interacting with environmental situations that present space-time variations and that involve contact with other life forms, which may behave as commensals or as invaders and/or ...
Carbone, Annalucia +3 more
core +1 more source
Influence of the extracellular matrix on cell-intrinsic circadian clocks
Journal of Cell Science, 2019 Cell-autonomous circadian clocks coordinate tissue homeostasis with a 24-hourly rhythm. The molecular circadian clock machinery controls tissue- and cell type-specific sets of rhythmic genes.
C. Streuli, Q. Meng
semanticscholar +1 more source
Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice
Medicina, 2022 Background and Objectives: The antidiabetic agent metformin is known to activate AMP-activated protein kinase (AMPK) in various tissues. Because AMPK can modulate intracellular circadian clocks through regulating the stability of clock components, a ...
Nazmul Hasan +7 more
doaj +1 more source
Enhanced precision of circadian rhythm by output system [PDF]
arXiv, 2022 Circadian rhythms are biological rhythms of approximately 24 h that persist even under constant conditions without environmental daily cues. The molecular circadian clock machinery generates the physiological rhythms, which can be transmitted into the downstream output system. Owing to the stochastic nature of the biochemical reactions, the oscillation
arxiv
Circadian Organization in Hemimetabolous Insects [PDF]
, 2004 The circadian system of hemimetabolous insects is reviewed in respect to the locus of the circadian clock and multioscillatory organization. Because of relatively easy access to the nervous system, the neuronal organization of the clock system in ...
Abe Y. +17 more
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Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment
Journal of Cell Science, 2018 The circadian clock is an autonomous molecular feedback loop inside almost every cell in the body. We have shown that the mammary epithelial circadian clock is regulated by the cellular microenvironment. Moreover, a stiff extracellular matrix dampens the
Jack L. Williams +5 more
semanticscholar +1 more source
Glucocorticoids and the circadian clock [PDF]
Journal of Endocrinology, 2008 Glucocorticoids, hormones produced by the adrenal gland cortex, perform numerous functions in body homeostasis and the response of the organism to external stressors. One striking feature of their regulation is a diurnal release pattern, with peak levels linked to the start of the activity phase. This release is under control of the circadian clock, an
openaire +4 more sources
Circadian rhythms in thrombosis and atherothrombotic events
Frontiers in Bioscience-Landmark, 2022 Biological circadian rhythms in living organisms are regulated by molecular clocks. Several of these clocks are present in blood vessels, peripheral tissues, and immune cells.
Eduardo Peñaloza-Martínez +7 more
doaj +1 more source
Design Principles of Phosphorylation-Dependent Timekeeping in Eukaryotic Circadian Clocks.
Cold Spring Harbor Perspectives in Biology, 2018 The circadian clock in cyanobacteria employs a posttranslational oscillator composed of a sequential phosphorylation-dephosphorylation cycle of KaiC protein, in which the dynamics of protein structural changes driven by temperature-compensated KaiC's ...
K. Ode, H. Ueda
semanticscholar +1 more source