Results 81 to 90 of about 336,986 (421)
The circadian clock goes genomic [PDF]
Genome Biology, 2013 Large-scale biology among plant species, as well as comparative genomics of circadian clock architecture and clock-regulated output processes, have greatly advanced our understanding of the endogenous timing system in plants.
Staiger, Dorothee +3 more
openaire +5 more sources
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
Circadian and Circalunar Clock Interactions in a Marine Annelid
Cell Reports, 2013 Life is controlled by multiple rhythms. Although the interaction of the daily (circadian) clock with environmental stimuli, such as light, is well documented, its relationship to endogenous clocks with other periods is little understood.
Juliane Zantke +8 more
doaj +1 more source
An adipokine feedback regulating diurnal food intake rhythms in mice
eLife, 2020 Endogenous circadian clocks have evolved to anticipate 24 hr rhythms in environmental demands. Recent studies suggest that circadian rhythm disruption is a major risk factor for the development of metabolic disorders in humans. Conversely, alterations in
Anthony H Tsang +4 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Sleep is regulated by circadian and homeostatic processes. Whereas the suprachiasmatic nucleus (SCN) is viewed as the principal mediator of circadian control, the contributions of sub-ordinate local circadian clocks distributed across the brain are ...
Elizabeth Susan Maywood +4 more
doaj +1 more source
Optimal implementations for reliable circadian clocks [PDF]
Physical Review Letters, 113, 108101 (2014), 2014 Circadian rhythms are acquired through evolution to increase the chances for survival through synchronizing with the daylight cycle. Reliable synchronization is realized through two trade-off properties: regularity to keep time precisely, and entrainability to synchronize the internal time with daylight.
arxiv +1 more source
Circadian regulation of lipid mobilization in white adipose tissues. [PDF]
, 2013 In mammals, a network of circadian clocks regulates 24-h rhythms of behavior and physiology. Circadian disruption promotes obesity and the development of obesity-associated disorders, but it remains unclear to which extent peripheral tissue clocks ...
Meyer-Kovac, J., Oster, H., Shostak, A.
core +2 more sources
Annals of the Rheumatic Diseases, 2016 Objectives The circadian clocks are internal timing mechanisms that drive ∼24-hour rhythms in a tissue-specific manner. Many aspects of the physiology of the intervertebral disc (IVD) show clear diurnal rhythms.
M. Dudek +12 more
semanticscholar +1 more source
The circadian clock and behavior
Behavioural Brain Research, 2001 Temporal organization is a fundamental feature of all living systems. Timing is essential for development, growth and differentiation and in the mature organism, it is essential to maintain normal physiology and behavior. The biological entity that permits an organism's day/night organization is the circadian system.
Urs Albrecht, Henrik Oster
openaire +3 more sources
Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source