Results 141 to 150 of about 31,091 (262)

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Advances in CircRNAs in the Past Decade: Review of CircRNAs Biogenesis, Regulatory Mechanisms, and Functions in Plants

Circular RNA (circRNA) is a type of non-coding RNA with multiple biological functions. Whole circRNA genomes in plants have been identified, and circRNAs have been demonstrated to be widely present and highly expressed in various plant tissues and organs.
Libo Zhang, Nazeer Ahmed, Jing-Jiang Zhou, Yue Ma, Ding Yang, Misbah Naz, Zhuo Chen, Dongqin Zhang   +7 more
core   +2 more sources

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

The genomic character and conservation of circRNAs.

, 2018
(A) Mean length distribution of upstream and downstream intron flanking circularized exons in Z.mays. Longer intron bracketing circularized exons was observed than the parent gene.
Yanfeng Zhu (6069461), Guanglin Li (709617), Hua Zhang (12549), Zhiqiang Hao (709613), Baihua Tang (6069458)   +4 more
core   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

CircRNA: Functions, Applications and Prospects

Biomolecules
Circular RNAs (circRNAs) represent a distinct class of covalently closed non-coding RNA molecules characterized by the absence of free 5′ and 3′ ends [...]
Fei Xu, Qing Xiao, William W. Du, Sheng Wang, Burton B. Yang   +4 more
openaire   +3 more sources

Synergistic Immunoregulation: harnessing CircRNAs and PiRNAs to Amplify PD-1/PD-L1 Inhibition Therapy

Rui Han,1,2 Xiwu Rao,3 Huiling Zhou,4 Lingeng Lu5– 7 1Department of Chinese Medicine Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, People’s Republic of China; 2Department of Chinese Medicine, Naval Medical University ...
Lu L, Han R, Rao X, Zhou H
core  

Genome–phenome association prediction using weighted deep matrix factorization with a multisource graph attention network

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Genome–phenome association (GPA) prediction can broaden the understanding of biological mechanisms underlying complex phenotypic traits (e.g., diseases and agronomic traits). Traditional deep matrix factorization (DMF)‐based GPA methods can integrate multiple data types and uncover nonlinear associations but often rely on low‐dimensional ...
Ran Duan, Wei Cao, Maozu Guo, Le Tian, Lingling Zhao   +4 more
wiley   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Percentages of the four types circRNAS.

, 2018
Percentages of the four types circRNAS.
Youhong Chang (113440), Hong Wang (13528), Xiaogang Li (299205), Jinxing Wang (4952113), Jing Lin (50818), Hui Li (32376), Qingsong Yang (491467)   +6 more
core   +1 more source