Results 1 to 10 of about 2,008,153 (347)

Cell-type specific features of circular RNA expression. [PDF]

open access: yesPLoS Genetics, 2013
Thousands of loci in the human and mouse genomes give rise to circular RNA transcripts; at many of these loci, the predominant RNA isoform is a circle. Using an improved computational approach for circular RNA identification, we found widespread circular
Julia Salzman   +4 more
doaj   +2 more sources

Expression Significance of Serum Circular RNA CDYL and Circular RNA ROBO2 in Patients with Acute Myocardial Infarction and the Value of Their Combined Prediction for Major Adverse Cardiovascular Events [PDF]

open access: yesInternational Journal of General Medicine
Fang Wang, Rui Liu, Cuirong Zhang, Shenglin Liu Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, People’s Republic of ChinaCorrespondence: Shenglin Liu, Email isl0076@163.comObjective: To ...
Wang F, Liu R, Zhang C, Liu S
doaj   +2 more sources

Circular RNA in hepatocellular carcinoma: emerging therapeutic strategies [PDF]

open access: yesFrontiers in Immunology
Circular RNAs, or circRNAs, are unique single-stranded RNA molecules that form covalently closed circles. They possess a wide range of cellular functions and can act as tumor suppressors or promoters, regulating various aspects of carcinogenesis.
Gregor Jazbec, Tadeja Režen
doaj   +2 more sources

Research progress on circular RNA vaccines

open access: yesFrontiers in Immunology, 2023
Owing to the success of linear mRNA coronavirus disease 2019 (COVID-19) vaccines, biopharmaceutical companies and research teams worldwide have attempted to develop more stable circular RNA (circRNA) vaccines and have achieved some preliminary results ...
Yu Bai   +17 more
doaj   +2 more sources

Closing the circle : current state and perspectives of circular RNA databases [PDF]

open access: yes, 2021
Circular RNAs (circRNAs) are covalently closed RNA molecules that have been linked to various diseases, including cancer. However, a precise function and working mechanism are lacking for the larger majority.
Vandesompele, Jo   +2 more
core   +1 more source

Detecting circular RNA from high-throughput sequence data with de Bruijn graph

open access: yesBMC Genomics, 2020
Background Circular RNA is a type of non-coding RNA, which has a circular structure. Many circular RNAs are stable and contain exons, but are not translated into proteins.
Xin Li, Yufeng Wu
doaj   +1 more source

A linear and circular dual-conformation noncoding RNA involved in oxidative stress tolerance in Bacillus altitudinis

open access: yesNature Communications, 2023
Circular RNAs have been extensively studied in eukaryotes, but their presence and/or biological functionality in bacteria are unclear. Here, we show that a regulatory noncoding RNA (DucS) exists in both linear and circular conformation in Bacillus ...
Ting-Ting He   +10 more
doaj   +1 more source

Circular RNA in tumor metastasis

open access: yesMolecular Therapy: Nucleic Acids, 2021
Circular RNAs (circRNAs) are a type of endogenous non-coding RNA that were discovered to regulate gene expression through multiple pathways. Metastasis remains one of the biggest obstacles in cancer treatment.
Chao Zhang   +9 more
doaj   +1 more source

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