Results 11 to 20 of about 1,797,821 (330)
Circular RNA HIPK3: A Key Circular RNA in a Variety of Human Cancers [PDF]
Frontiers in Oncology, 2020 Circular RNAs (circRNAs), which act as initiators and promoters of various diseases, were thought to be mostly noncoding RNAs (ncRNAs) in eukaryotes, until recent studies confirmed that some circRNAs have the function of encoding proteins.
Jingyuan Wen +5 more
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Circular RNA—Is the Circle Perfect?
Biomolecules, 2021 Circular RNA (circRNA) is a distinct class of non-coding RNA produced, in principle, using a back-splicing mechanism, conserved during evolution, with increased stability and a tissue-dependent expression.
Lavinia Caba +4 more
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Circular RNA in gastric cancer
Chinese Medical Journal, 2020 . Gastric cancer (GC) is a common malignancy and is the third leading cause of cancer-related death. At present, there is no simple and effective screening method for early-stage GC, and the treatment results and prognosis are poor.
Xue-Wei Li +3 more
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Circular RNA: Biosynthesis in vitro [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Circular RNA (circRNA) is a unique type of noncoding RNA molecule. Compared with traditional linear RNA, circRNA is a covalently closed circle produced by a process called backsplicing.
Xinjie Chen, Yuan Lu
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Circular RNA in Diseased Heart [PDF]
Cells, 2020 Heart disease remains the leading cause of death globally and leads to tremendous socio-economic burden. Despite advances in the field of cardiovascular research, novel theranostics are still in urgent need.
Ying Wang, Bin Liu
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Circular RNA and tumor microenvironment [PDF]
Cancer Cell International, 2020 Circular RNAs (circRNAs) are small non-coding RNAs with a unique ring structure and play important roles as gene regulators. Disturbed expressions of circRNAs is closely related to varieties of pathological processes.
Huixin Song, Qiaofei Liu, Quan Liao
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Circular RNA Regulation of Myogenesis [PDF]
Cells, 2019 Circular RNA (circRNA) is a novel class of non-coding RNA generated by pre-mRNA back splicing, which is characterized by a closed-loop structure. Although circRNAs were firstly reported decades ago, their regulatory roles have not been discovered until ...
Pengpeng Zhang +10 more
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Circular RNA in tumor metastasis [PDF]
Molecular Therapy: Nucleic Acids, 2021 Circular RNAs (circRNAs) are a type of endogenous non-coding RNA that were discovered to regulate gene expression through multiple pathways. Metastasis remains one of the biggest obstacles in cancer treatment.
Chao Zhang +9 more
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Biogenesis of Circular RNAs [PDF]
Cell, 2014 Circular RNAs are generated during splicing through various mechanisms. Ashwal-Fluss et al. demonstrate that exon circularization and linear splicing compete with each other in a tissue-specific fashion, and Zhang et al. show that exon circularization depends on flanking intronic complementary sequences.
Quentin Vicens, Éric Westhof
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Circular RNAs in Toxicology [PDF]
Toxicological Sciences, 2020 Abstract Circular RNAs (circRNAs) are a type of closed, long, non-coding RNAs, which have attracted significant attention in recent years. CircRNAs exhibit unique functions and are characterized by stable expression in various tissues across different species.
Yueting Shao, Yiguo Jiang
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