Results 31 to 40 of about 2,008,153 (347)

Encoding folding paths of RNA switches [PDF]

open access: yes, 2006
RNA co-transcriptional folding has long been suspected to play an active role in helping proper native folding of ribozymes and structured regulatory motifs in mRNA untranslated regions.
Harlepp, S.   +3 more
core   +3 more sources

Circular RNA vaccine in disease prevention and treatment

open access: yesSignal Transduction and Targeted Therapy, 2023
CircRNAs are a class of single-stranded RNAs with covalently linked head-to-tail topology. In the decades since its initial discovery, their biogenesis, regulation, and function have rapidly disclosed, permitting a better understanding and adoption of ...
Dun Niu, Yaran Wu, J. Lian
semanticscholar   +1 more source

Construction of a circRNA-miRNA-mRNA Regulated Pathway Involved in EGFR-TKI Lung Adenocarcinoma Resistance

open access: yesTechnology in Cancer Research & Treatment, 2021
Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM   +7 more
doaj   +1 more source

Sequence organization of feline leukemis virus DNA in infected cells [PDF]

open access: yes, 1980
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W.   +3 more
core   +1 more source

Circular RNA: A Potential Biomarker for Lung Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2019
Circular RNA is a non-coding RNA that acts as a sponge for RNA, regulates cleavage and transcription, translates proteins and interacts with RNA-binding proteins.
XIAO Zhihao   +3 more
doaj   +1 more source

Circular RNA and tumor microenvironment

open access: yesCancer Cell International, 2020
Circular RNAs (circRNAs) are small non-coding RNAs with a unique ring structure and play important roles as gene regulators. Disturbed expressions of circRNAs is closely related to varieties of pathological processes.
Huixin Song, Qiaofei Liu, Quan Liao
doaj   +1 more source

Circular RNA identified from Peg3 and Igf2r. [PDF]

open access: yesPLoS ONE, 2018
Circular RNA is a newly discovered class of non-coding RNA generated through the back-splicing of linear pre-mRNA. In the current study, we characterized two circular RNAs that had been identified through NGS-based 5'RACE experiments.
Bambarendage P U Perera   +2 more
doaj   +1 more source

A small RNA response at DNA ends in Drosophila [PDF]

open access: yes, 2012
Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently ...
Böttcher, Romy   +2 more
core   +1 more source

Circular RNA-protein interactions: functions, mechanisms, and identification

open access: yesTheranostics, 2020
Circular RNAs (circRNAs) are covalently closed, endogenous RNAs with no 5′ end caps or 3′ poly(A) tails. These RNAs are expressed in tissue-specific, cell-specific, and developmental stage-specific patterns.
Anqing Huang   +4 more
semanticscholar   +1 more source

CiLiQuant: Quantification of RNA Junction Reads Based on Their Circular or Linear Transcript Origin

open access: yesFrontiers in Bioinformatics, 2022
Distinguishing circular RNA reads from reads derived from the linear host transcript is a challenging task because of sequence overlap. We developed a computational approach, CiLiQuant, that determines the relative circular and linear abundance of ...
Annelien Morlion   +13 more
doaj   +1 more source

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