Investigation of the association between circulating inflammatory proteins and encephalitis risk in Europeans by two-sample Mendelian randomization analysis [PDF]
Frontiers in NeurologyBackgroundCytokines are powerful immune response factors that operate at inflammation sites and are also found in the blood. Nevertheless, research on encephalitis and these circulating inflammatory proteins is quite limited.MethodsThis study ...
Yanwei Liu +4 more
doaj +7 more sources
The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD [PDF]
International Journal of COPDKunrong Yan, Yingjian Wang, Peng Xin Department of Anaesthesia, Chaoyang Second Hospital, Chaoyang, Liaoning, People’s Republic of ChinaCorrespondence: Peng Xin, Email cy08xp@163.comObjective: Observational studies have indicated that immune cells and ...
Yan K, Wang Y, Xin P
doaj +7 more sources
Mendelian randomization analysis of causal and druggable circulating inflammatory proteins in schizophrenia [PDF]
Frontiers in PsychiatryBackgroundSchizophrenia (SZ) is a severe mental disorder with complex origins. Observational studies suggested that inflammatory factors may play a role in the pathophysiology of SZ and we aim to investigate the potential genetic connection between them ...
Hongbao Cao +6 more
doaj +6 more sources
Identification of Druggable Targets for Alzheimer's Disease by Analyzing Circulating Inflammatory Proteins With Mendelian Randomization [PDF]
Brain and BehaviorObjective To identify potential druggable targets for Alzheimer's disease (AD) by analyzing circulating inflammatory proteins using Mendelian randomization (MR).
Hongliang An, Jianhong Gu, Taiping Li
doaj +5 more sources
Evaluating the effects of circulating inflammatory proteins as drivers and therapeutic targets for severe COVID-19 [PDF]
Frontiers in ImmunologyObjectiveThe relationships between circulating inflammatory proteins and COVID-19 have been observed in previous cohorts. However, it is not unclear which circulating inflammatory proteins may boost the risk of or protect against COVID-19.MethodsWe ...
Ancha Baranova +7 more
doaj +7 more sources
Exploring the association between 91 circulating inflammatory proteins and the risk of carcinoid syndrome: a Mendelian randomization analysis [PDF]
Discover OncologyThis study aims to explore the potential correlation between circulating inflammatory proteins and carcinoid syndrome (CS). Using summary data from genome-wide association studies (GWAS), we conducted a Mendelian randomization (MR) analysis with two ...
Jingzhi Wang, Simin Peng
doaj +5 more sources
Plasma lipidome, circulating inflammatory proteins, and Parkinson’s disease: a Mendelian randomization study [PDF]
Frontiers in Aging NeuroscienceBackgroundObservational studies have suggested that plasma lipidome play a pivotal role in the occurrence of Parkinson’s disease (PD). However, it remains unknown which lipids among plasma lipidome affect PD and how they exert their influence. Clarity is
Yidan Qin +5 more
doaj +6 more sources
The mediation of circulating inflammatory proteins in the causal pathway from immune cells to osteoarthritis [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Observational studies have found that immune cells and circulating inflammatory proteins play a dual role in the progression of osteoarthritis, but the exact mechanism remains unclear.
Ye Yuan +3 more
doaj +5 more sources
Association and mediation between circulating inflammatory proteins and skin fibrosis [PDF]
Frontiers in EndocrinologyObjectiveSkin fibrosis is a dermal lesion associated with inflammatory factors. However, the exact causal relationship between circulating inflammatory proteins (CIPs) and skin fibrosis remains unclear.
Zirui Zhao +8 more
doaj +4 more sources
Unveiling the Intricate Causal Nexus Between 91 Circulating Inflammatory Proteins and Perianal Abscess Through a Comprehensive Bidirectional Two‐Sample Mendelian Randomization Analysis [PDF]
Health Science ReportsBackground The link between circulating inflammatory proteins and perianal abscess remains uncertain. This study utilized the Mendelian randomization approach to examine the potential causality of 91 circulating inflammatory proteins in relation to ...
Zehui Wang +4 more
doaj +4 more sources