Results 41 to 50 of about 256,540 (247)

Circulating inflammatory proteins and osteomyelitis: A bidirectional Mendelian randomization and colocalization analysis. [PDF]

Medicine (Baltimore)
Circulating inflammatory proteins (CIPs) have been implicated in the progression of osteomyelitis (OM); however, whether these proteins play a causal role or are merely a consequence remains unclear. This study aimed to assess the causal relationships between CIPs and OM using a bidirectional 2-sample Mendelian randomization (MR) approach.
Feng T, Chen P, Lin F.
europepmc   +3 more sources

Assessment of causality between circulating inflammatory proteins and subtypes of diabetic retinopathy. [PDF]

Int J Ophthalmol
AIM: To explore the causal links among circulating inflammatory proteins (CIPs) and the varying severities of diabetic retinopathy (DR). METHODS: This research utilized a two sample Mendelian randomization (MR) approach to explore the causal relationships between 91 CIPs and various severities of DR: background DR (BDR) or non-proliferative DR (NPDR ...
Dong M, Zhang NZ, Cao WY, Deng XX, Zhang WX, Xing YQ, Yang N.   +6 more
europepmc   +3 more sources

Causality Between 91 Circulating Inflammatory Proteins and Various Asthma Phenotypes: A Mendelian Randomization Study [PDF]

ImmunoTargets and Therapy
Shiyao Zhang,1 Xiuying Zhang,2 Chenghao Wei,1 Lai Zhang,1 Zhaoyang Li1 1Liaoning University of Traditional Chinese Medicine, Shenyang, 110847, People’s Republic of China; 2The First Affiliated Hospital of Liaoning University of Traditional Chinese ...
Zhang S, Zhang X, Wei C, Zhang L, Li Z
doaj   +2 more sources

Circulating inflammatory proteins predict dementia risk, and are linked to structural brain changes and modifiable risk factors. [PDF]

Alzheimers Res Ther
INTRODUCTION: Systemic inflammation has been identified as a key factor in neurodegeneration but the value of circulating inflammatory proteins in dementia risk prediction and their causal role has not been elucidated.
Abdolkarimi D, Liu Y, Gilchrist L, Calhas S, Waters S, Marshall CR, Proitsi P.   +6 more
europepmc   +3 more sources

Causal insights into multiple myeloma: The impact of circulating inflammatory proteins and metabolites. [PDF]

Medicine (Baltimore)
Multiple myeloma (MM) is a heterogeneous hematologic malignancy characterized by high recurrence rates and incurability despite therapeutic advances. Emerging evidence implicates circulating inflammatory proteins, plasma metabolites, and leukocyte characteristics in MM pathogenesis, though their specific causal roles remain unclear.
Zhang P, Li H, Huang Y, Sha H.
europepmc   +3 more sources

Circulating Fibroblast Activation Protein as Potential Biomarker in Patients With Inflammatory Bowel Disease [PDF]

Frontiers in Medicine, 2021
A major concern in the management of Inflammatory Bowel Disease (IBD) is the absence of accurate and specific biomarkers to drive diagnosis and monitor disease status timely and non-invasively. Fibroblast activation protein (FAP) represents a hallmark of IBD bowel strictures, being overexpressed in stenotic intestinal myofibroblasts.
Fabio Corsi, Fabio Corsi, Luca Sorrentino, Sara Albasini, Francesco Colombo, Maria Cigognini, Alessandro Massari, Carlo Morasso, Serena Mazzucchelli, Francesca Piccotti, Sandro Ardizzone, Sandro Ardizzone, Gianluca M. Sampietro, Marta Truffi   +13 more
openaire   +3 more sources

Association between circulating inflammatory proteins and recurrent spontaneous abortion

Chinese Medical Journal
Xianyang Hu, Tingxuan Yin, Min Yu, Xixi Huang, Hailin Yu, Lu Liu, Meirong Du, Jinjiao Li   +7 more
doaj   +2 more sources

Association between circulating inflammatory proteins and gout: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Clinical studies have consistently demonstrated that inflammation is a critical factor in the pathophysiology and progression of gout. This study aims to explore the causal relationship between CIPs and gout, utilizing MR in conjunction with meta-analyses.
Xie X, Song Y, Chen W, Zhao H, Chu N, Wang F.   +5 more
europepmc   +3 more sources

Longitudinal study of circulating protein biomarkers in inflammatory bowel disease [PDF]

Journal of Proteomics, 2015
Inflammatory bowel diseases (IBDs) are chronic and progressive inflammatory disorders of the gastrointestinal tract. In IBD, protein serological biomarkers could be relevant tools for assessing disease activity, performing early-stage diagnosis and managing the treatment.
Emilie Viennois, Mark T. Baker, Bo Xiao, Lixin Wang, Hamed Laroui, Didier Merlin   +5 more
openaire   +2 more sources

Genetics of Circulating Inflammatory Proteins and Iridocyclitis: An Exploratory Mendelian Randomization Study. [PDF]

Transl Vis Sci Technol
This study aimed to explore the potential causal relationship between genetically determined elevated levels of pro-inflammatory cytokines and iridocyclitis, including its subtypes: acute and subacute iridocyclitis (ASIR) and chronic iridocyclitis (CIR).A two-sample Mendelian randomization (MR) analysis was conducted using genome-wide association study
Liu H, Li F, Wang F, Hu Z, Du L, Wei J.
europepmc   +3 more sources