Results 31 to 40 of about 256,540 (247)

Gut microbiota, circulating inflammatory proteins and sepsis: a bi-directional Mendelian randomization study

Frontiers in Cellular and Infection Microbiology
BackgroundGut microbiota is closely related to the occurrence and development of sepsis. However, the causal effects between the gut microbiota and sepsis, and whether circulating inflammatory proteins act as mediators, remain unclear.MethodsGut ...
Zuming Li, Liangcai Lin, Yunqi Kong, Jieni Feng, Xiaolei Ren, Yushi Wang, Xueru Chen, Siyi Wu, Rongyuan Yang, Rongyuan Yang, Jiqiang Li, Jiqiang Li, Jiqiang Li, Yuntao Liu, Yuntao Liu, Yuntao Liu, Yuntao Liu, Yue Lu, Yue Lu, Yue Lu, Yue Lu, Jiankun Chen, Jiankun Chen, Jiankun Chen   +23 more
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Exploration of the causal associations between circulating inflammatory proteins, immune cells, and neuromyelitis optica spectrum disorder: a bidirectional Mendelian randomization study and mediation analysis [PDF]

Frontiers in Aging Neuroscience
BackgroundAn increasing body of research has demonstrated a robust correlation between circulating inflammatory proteins and neuromyelitis optica spectrum disorders (NMOSD).
Zhiqing Chen, Yujin Guo, Huaiyu Sun, Wuqiong Zhang, Shuai Hou, Yu Guo, Xiaohui Ma, Hongmei Meng   +7 more
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Two-sample Mendelian randomization analysis of 91 circulating inflammatory protein levels and amyotrophic lateral sclerosis [PDF]

Frontiers in Aging Neuroscience
IntroductionAmyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood pathophysiology. Recent studies have highlighted systemic inflammation, especially the role of circulating inflammatory proteins, in ALS.MethodsThis ...
Chenxu Xiao, Xiaochu Gu, Yu Feng, Yu Feng, Jing Shen   +4 more
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Causal associations of circulating inflammatory proteins with sepsis: a two-sample Mendelian randomization study [PDF]

Archives of Medical Science
Introduction Sepsis arises from dysregulated inflammation in response to infection, precipitating organ dysfunction. Circulating inflammatory mediators likely contribute to sepsis pathogenesis, but their precise roles remain unclear. We aimed to evaluate
Dandan Ji, Jiawei Ma, Jing Ma, Jia Wu
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Causal association between circulating inflammatory proteins and peripheral artery disease: a bidirectional two-sample Mendelian randomization study

Frontiers in Immunology
IntroductionA growing body of research has shown a strong connection between circulating inflammatory proteins and Peripheral artery disease (PAD). However, the causal relationship between circulating inflammatory proteins and PAD is still not fully ...
Juncheng Zhao, Bo Sun, Shujie Huang, Yunhui Chen, Jingqiang Yan   +4 more
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Association between circulating inflammatory proteins and benign prostatic disease: a Mendelian randomization study

Scientific Reports
Previous research has suggested that circulating inflammatory proteins are associated with benign prostatic disease (BPD). This Mendelian randomization (MR) study was conducted to further investigate the causal relationship between 91 inflammatory ...
Hongliang Cao, Chengdong Shi, Zulipikaer Aihemaiti, Xianyu Dai, Fulin Wang, Song Wang   +5 more
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The genetic relationships between immune cell traits, circulating inflammatory proteins and preeclampsia/eclampsia

Frontiers in Immunology
ObjectivesPreeclampsia/eclampsia (PE), a critical complication during pregnancy, has been suggested to correlate with immune cell phenotypes and levels of circulating inflammatory proteins.
Yu Liu, Yu Liu, Yuliang Zhang, Yuliang Zhang, Lili Du, Lili Du, Dunjin Chen, Dunjin Chen   +7 more
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Effects of circulating inflammatory proteins on osteoporosis and fractures: evidence from genetic correlation and Mendelian randomization study

Frontiers in Endocrinology
ObjectiveThere is a controversy in studies of circulating inflammatory proteins (CIPs) in association with osteoporosis (OP) and fractures, and it is unclear if these two conditions are causally related.
Qingcong Zheng, Du Wang, Rongjie Lin, Zhechen Li, Yuchao Chen, Rongsheng Chen, Chunfu Zheng, Weihong Xu   +7 more
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Metabolic biomarkers mediate allergic rhinitis via circulating inflammatory proteins: Evidence from a Mendelian randomization study [PDF]

Brazilian Journal of Otorhinolaryngology
Objective: Allergic Rhinitis (AR), a prevalent allergic condition, markedly diminishes quality of life and increases public health burdens. This study investigated the mediating roles of Metabolic Biomarkers (MBs) in the associations between Circulating ...
Xiang Cao, Boyang Zhang, Wei Wang, Zijiao Xu, Zhixin Jiang   +4 more
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Causal Association Between Circulating Inflammatory Proteins and Autoimmune Liver Disease: a Bidirectional Two-Sample Mendelian Randomization Study [PDF]

ImmunoTargets and Therapy
Lina Leng,1,* Ying Li,2,* Tao Xu,3 Jingfang Shen,1 Lianju Li,1 Xiaoli Li1 1Department of Rheumatology, Xingtai People’s Hospital, Xingtai, 054001, Hebei Province, People’s Republic of China; 2Department of Oncology, 82 Group Hospital of Chinese ...
Leng L, Li Y, Xu T, Shen J, Li L, Li X
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