Mendelian Randomization Analysis Supports a Causal Relationship Between Circulating Inflammatory Proteins and Basal Cell Carcinoma [PDF]
Clinical, Cosmetic and Investigational DermatologyZhi-da Fu,1,2,* Yao Wang,3,* Hong-li Yan,2 Jian-hua Wu1 1Department of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 2Center for Reproductive Medicine, Changhai Hospital, Naval Medical University,
Fu ZD, Wang Y, Yan HL, Wu JH
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The Role of Gut Microbiota on Idiopathic Pulmonary Fibrosis Mediated by Circulating Inflammatory Proteins: A Two‐Step, Two‐Sample Mendelian Randomization Study [PDF]
The Clinical Respiratory JournalBackground Persistent inflammation is a crucial characteristic of idiopathic pulmonary fibrosis (IPF). Gut microbiota (GM) contribute to the occurrence and development of several pulmonary diseases through the “gut–lung axis.” The genetic role of GM in ...
Hongyu Zhu +4 more
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The Mediation of Circulating Inflammatory Proteins in the Causal Pathway From Immune Cells to Delirium [PDF]
Brain and BehaviorObjective: Observational research indicates that immune cells, in conjunction with circulating inflammatory proteins, could serve two functions in the development of delirium, despite the fact that the exact mechanisms remain ambiguous.
Tongshuai Liu +3 more
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Rheumatoid Arthritis, Circulating Inflammatory Proteins, and Hypertension: A Mendelian Randomization Study [PDF]
The Journal of Clinical HypertensionObservational studies have indicated that there is an association between rheumatoid arthritis (RA) and an elevated risk of hypertension. However, a definitive causal relationship between the two conditions has not been established. The objective of this
Guobing Jia +3 more
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Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma [PDF]
EBioMedicine, 2022 Summary: Background: Inflammation can modulate tumour growth and progression, and influence clinical response to treatment. We investigated the potential of circulating inflammatory proteins for response stratification of immune checkpoint inhibitor ...
Niccolò Rossi +25 more
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The Causal Effects Between Circulating Inflammatory Proteins and Osteoarthritis: A Mendelian Randomization and Transcriptomic Analysis [PDF]
Journal of Pain ResearchShaoru Lin,1 Changwu Wu,2,3 Yimin Pan2 1Department of Orthopedics, The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, People’s Republic of China; 2Department of Neurosurgery, Xiangya Hospital, Central South ...
Lin S, Wu C, Pan Y
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The Effect of Circulating Inflammatory Proteins on Endometriosis: A Mendelian Randomization Study. [PDF]
Immunotargets TherEndometriosis is a complex gynecological condition in which endometrial fragments are implanted outside the uterus, causing pain and infertility. Although immune mediators play a vital role in endometriosis, their exact etiology remains elusive. Using Mendelian randomization (MR), this study aimed to assess the causal relationship between inflammatory ...
Wei Y, Zhao X, Li L.
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Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer [PDF]
Scientific Reports, 2018 AbstractAlthough inflammation is central to gallbladder cancer (GBC) development and proliferation, no study has systematically investigated circulating inflammatory proteins and patient survival. We aimed to examine whether the circulating levels of inflammatory proteins is associated with all-cause mortality among such patients.
Zhiwei Liu +15 more
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Genetics of causal relationships between circulating inflammatory proteins and postherpetic neuralgia: a bidirectional Mendelian randomization study [PDF]
Frontiers in NeurologyObjectiveAccording to data from several observational studies, there is a strong association between circulating inflammatory cytokines and postherpetic neuralgia (PHN), but it is not clear whether this association is causal or confounding; therefore ...
WenHui Liu +5 more
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Relationship Among Circulating Inflammatory Proteins, Platelet Gene Expression, and Cardiovascular Risk [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013 Objective— Cardiovascular disease is a complex disorder influenced by interactions of genetic variants with environmental factors. However, there is no information from large community-based studies examining the relationship of circulating cell–specific RNA to inflammatory proteins.
McManus, David D +7 more
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