Circulating Profile of ECM-Related Proteins as Diagnostic Markers in Inflammatory Bowel Diseases
The aim of our research was to find new biomarkers that could be potentially used in the diagnosis, differentiation and monitoring of inflammatory bowel diseases (IBD). Since extracellular matrix (ECM) remodeling contributes to the pathological changes occurring in IBD, the serum profile of ECM-related proteins may reflect disease activity in the ...
Katarzyna Komosinska-Vassev +4 more
openaire +2 more sources
Differential regulation of circulating levels of molecular chaperones in patients undergoing treatment for periodontal disease. [PDF]
Evidence is emerging that molecular chaperones, in addition to their intracellular protein folding actions, can act as intercellular signaling proteins with an ability to modulate leukocyte function. Recent evidence has also shown that these proteins can
Alireza Shamaei-Tousi +24 more
core +1 more source
Abstract Background and Objective Tinnitus would benefit from an objective biomarker. The goal of this study is to identify plasma biomarkers of constant and chronic tinnitus among selected circulating inflammatory proteins.
Christopher R. Cederroth +12 more
openaire +5 more sources
Influenza vaccination downregulates circulating inflammatory proteins. [PDF]
A. Principal component analysis (PCA) of circulating proteins belonging to 10 participants before and after vaccination. The mean difference between before and after in PC1 was calculated by Wilcoxon signed-rank test. B.
Simone J. C. F. M. Moorlag (11247795) +23 more
core +1 more source
Circulating PAMM, a novel antioxidant and anti-inflammatory protein, is elevated in acute SCI [PDF]
Abstract Background Peroxiredoxin activated in M-CSF stimulated monocytes (PAMM) is a novel protein produced by adipocytes with putative redox regulatory and anti-inflammatory properties. Because acute spinal cord injury (SCI) is associated with oxidative stress and neuroinflammation and because PAMM can be detected in systemic circulation, we ...
Leslie R. Morse +4 more
openaire +3 more sources
Moderate alcohol consumption alters both leucocyte gene expression profiles and circulating proteins related to immune response and lipid metabolism in men [PDF]
Moderate alcohol consumption has various effects on immune and inflammatory processes, which could accumulatively modulate chronic disease risk. So far, no comprehensive, integrative profiling has been performed to investigate the effects of longer-term ...
Hendriks, H.F.J. +4 more
core +1 more source
Gingivitis is an extremely common oral inflammatory condition and can be induced in humans using an acute 21-day experimental gingivitis model. Neutrophils are known to be highly prevalent in the gingival crevice during gingival inflammation; however, the effect of gingivitis and the associated biofilm on peripheral blood neutrophils (PBN) is not well ...
Helen M. Roberts +4 more
openaire +2 more sources
Neutrophil extracellular traps in inflammatory disorders [PDF]
A novel feature of polymorphonuclear granulocyte (PMN) biology is their ability to generate neutrophil extracellular traps (NETs) via a distinct process of cell death termed NETosis.
Sur Chowdhury, Chanchal
core +1 more source
IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections. [PDF]
The host inflammatory response against infections is characterized by the release of pro-inflammatory cytokines and acute-phase proteins, driving both innate and adaptive arms of the immune response.
Jeroen Slaats +3 more
doaj +1 more source
A Mendelian randomized study on the correlation between 91 inflammatory protein levels and the risk of acute myeloid leukemia [PDF]
Objective The study aims to analyze the correlation between circulating inflammatory proteins and the risk of acute myeloid leukemia (AML). Methods AML data were obtained from the FinnGen alliance as the outcome. The Genome-wide Association Studies (GWAS)
AN Huihui, WU Tao, LIU Wenhui, TIAN Sirui
doaj +1 more source

