Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Peter Fraunberger +9 more
core +1 more source
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets. [PDF]
Circulating proteins have important functions in inflammation and a broad range of diseases. To identify genetic influences on inflammation-related proteins, we conducted a genome-wide protein quantitative trait locus (pQTL) study of 91 plasma proteins ...
Klareskog, Lars +148 more
core +8 more sources
Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study [PDF]
BACKGROUND AND PURPOSE: Previous work has shown that soluble heat shock protein 60 (HSP60; sHSP60), present in circulating blood, is associated with carotid atherosclerosis.
Mandal, K +20 more
core +1 more source
Causal Association of Plasma Lipidome With Inflammatory Bowel Diseases and Mediating Role of Circulating Inflammatory Proteins: A Mendelian Randomization Study. [PDF]
ABSTRACT The existing studies indicate that the lipidome may be associated with inflammatory bowel disease (IBD). However, most of the results of previous studies are based on epidemiological or observational studies. Meanwhile, the causal association between different lipids and inflammatory bowel diseases, as well as whether ...
Yin L, Zhu Y, Kong F, Tu H, Zhang B.
europepmc +3 more sources
Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Josiah I. Chung +55 more
core +1 more source
BackgroundPrevious studies have suggested that gut microbiota (GM) may be involved in the pathogenesis of epilepsy through the microbiota-gut-brain axis (MGBA).
Han Yang +15 more
doaj +1 more source
Examination of the inflammatory nature of different placental syncytiotrophoblast microparticles (STBM) preparations on human monocytes [PDF]
Background: Healthy human pregnancies are accompanied by a mild systemic maternal inflammatory response, which includes activation of peripheral blood monocytes.
Messerli, Marianne Simone
core +1 more source
Exploring the Causal Association Between 91 Circulating Inflammatory Proteins and Neurodegenerative Diseases: A Bidirectional Two‐Sample Mendelian Randomization and Bioinformatics Analysis [PDF]
Gong Ziwei
exaly +2 more sources
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source

