Results 21 to 30 of about 6,850,236 (255)

Tumor-derived circulating endothelial cell clusters in colorectal cancer. [PDF]

Science Translational Medicine, 2016
Clusters of tumor cells are often observed in the blood of cancer patients. These structures have been described as malignant entities for more than 50 years, although their comprehensive characterization is lacking.
Suhaimi, Nur-Afidah Mohamed, Ying, Jackie Y, van Dam, Rob M, Cima, Igor, Sengupta, Debarka, Alexander, Irina, Tai, Joyce A, Tan, Joanna H, Robson, Paul, Hillmer, Axel M, Hu, Min, Ten, Rachel, Prabhakar, Shyam, Koh, Poh Koon, Lim, Wei-Yen, Chew, Min Hoe, Goh, Wei Lin, Hauser, Charlotte A E, Iliescu, Ciprian, Tan, Iain B, Vo, Jess H, Lim, Bing, Lee, Daniel, Kong, Say Li, Chua, Clarinda, Lim, Wan Jun, Hauser, Charlotte, Rahmani, Mehran, Tan, Min-Han, Phyo, Wai Min, Hauser, Charlotte A. E., Tai, Joyce A., van Dam, Rob M., Tan, Joanna H., Hillmer, Axel M., Tan, Iain B., Ying, Jackie Y., Vo, Jess H.   +37 more
core   +5 more sources

Bring along your friends: Homotypic and heterotypic circulating tumor cell clustering to accelerate metastasis

Biomedical Journal, 2020
Metastasis formation is a hallmark of invasive cancers and it is achieved through the shedding of circulating tumor cells (CTCs) from the primary site into the blood circulation.
Nicola Aceto
doaj   +2 more sources

Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells [PDF]

Cell Reports, 2020
Circulating tumor cells (CTCs) are shed from solid cancers in the form of single or clustered cells, and the latter display an extraordinary ability to initiate metastasis.
Vetter, Marcus, Kunz, Leo, Donato, Cinzia, Heusermann, Wolf, Rochlitz, Christoph, Beisel, Christian, Banfi, Andrea, Di Maggio, Nunzia, Strittmatter, Karin, Szczerba, Barbara M., Weber, Walter Paul, Schroeder, Timm, Castro-Giner, Francesc, Weber, Walter P., Paasinen-Sohns, Aino, Scherrer, Ramona, Biehlmaier, Oliver, Szczerba, Barbara Maria, Aceto, Nicola, Di Maggio N, Beisel C, Schroeder T, Banfi A, Heusermann W, Castro-Giner F, Vetter M, Scherrer R, Donato C, Szczerba BM, Kunz L, Weber WP, Paasinen-Sohns A, Aceto N, Biehlmaier O, Rochlitz C, Strittmatter K   +35 more
core   +7 more sources

Single-cell resolution characterization of circulating tumor cell clusters [PDF]

, 2019
Metastatic dissemination is responsible for more than 90% of cancer-related deaths. However, the molecular features underlying the metastatic process are largely uncharacterized.
Szczerba, Barbara
core   +3 more sources

Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters

APL Bioengineering, 2022
Circulating tumor cell (CTC) clusters that are shed from the primary tumor into the bloodstream are associated with a poor prognosis, elevated metastatic potential, higher proliferation rate, and distinct molecular features compared to single CTCs ...
Celine Macaraniag, Qiyue Luan, Jian Zhou, Ian Papautsky   +3 more
doaj   +3 more sources

Circulating tumor cell clusters and circulating tumor cell-derived explant models as a tool for treatment response

BioTechniques, 2020
Biderahalli Kruthika Prasanna, Ajay Balakrishnan, Prashant Kumar   +2 more
doaj   +3 more sources

The Presence of Circulating Tumor Cell Cluster Characterizes an Aggressive Hepatocellular Carcinoma Subtype [PDF]

Frontiers in Oncology, 2021
BackgroundGrowing evidence suggests that circulating tumor cell (CTC) clusters may be an important factor in the metastatic process, but their role in hepatocellular carcinoma (HCC) remains unclear.
Jing-Jing Yu, Chang Shu, Hui-Yuan Yang, Zhao Huang, Ya-Ni Li, Ran Tao, Yue-Yue Chen, Qian Chen, Xiao-Ping Chen, Wei Xiao   +9 more
doaj   +3 more sources

Potential role of circulating tumor cells and cell-free DNA as biomarkers in oral squamous cell carcinoma: A prospective single-center study.

PLoS ONE
Metastasis in patients with oral squamous cell carcinoma has been associated with a poor prognosis. However, sensitive and reliable tests for monitoring their occurrence are unavailable, with the exception of PET-CT. Circulating tumor cells and cell-free
Natsuki Eboshida, Atsuko Hamada, Mirai Higaki, Fumitaka Obayashi, Nanako Ito, Sachiko Yamasaki, Ryouji Tani, Tomoaki Shintani, Koichi Koizumi, Souichi Yanamoto   +9 more
doaj   +2 more sources

Circulating Tumor Cell Clusters Are Cloaked with Platelets and Correlate with Poor Prognosis in Unresectable Pancreatic Cancer. [PDF]

Cancers (Basel), 2021
Lim M, Park S, Jeong HO, Park SH, Kumar S, Jang A, Lee S, Kim DU, Cho YK.   +8 more
europepmc   +2 more sources

A method to quantitatively characterize the formation and dissociation of tumor cell clusters using light transmission aggregometry

Molecular Oncology
In this paper, we have modified the workflow of the traditional light transmission aggregometry (LTA) protocol to characterize tumor cell clusters in vitro in a quantifiable and multifaceted manner.
Regina Komal Kottana, Brian Schnoor, Anne‐Laure Papa   +2 more
doaj   +2 more sources