Results 41 to 50 of about 2,021,965 (393)
Frontiers in Cell and Developmental Biology, 2023 Background: Platelets are active players in hemostasis, coagulation and also tumorigenesis. The cross-talk between platelets and circulating tumor cells (CTCs) may have various pro-cancer effects, including promoting tumor growth, epithelial-mesenchymal ...
Zahra Eslami-S +33 more
doaj +1 more source
Full-Length mRNA-Seq from single cell levels of RNA and individual circulating tumor cells
Nature Biotechnology, 2012 Genome-wide transcriptome analyses are routinely used to monitor tissue-, disease- and cell type–specific gene expression, but it has been technically challenging to generate expression profiles from single cells.
D. Ramsköld +11 more
semanticscholar +1 more source
Application of circulating tumor cells scope technique on circulating tumor cell research [PDF]
Molecular and Cellular Therapies, 2014 Circulating tumor cells (CTCs) are becoming promising biomarkers in several cancers, such as colon, prostate, and breast carcinomas. Independent research groups have reported a correlation between CTC numbers and patient prognosis. Even more, the development of personalized medicine gives physicians impetus to utilize the advancement of molecular ...
Xiaochen Tian, Lijie Wang, Dawei Yang
openaire +3 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Isolation of sufficient numbers of circulating tumor cells (CTCs) in cancer patients could provide an alternative to invasive tumor biopsies, providing multianalyte cell-based biomarkers that are not available from current plasma circulating
Avanish Mishra +13 more
semanticscholar +1 more source
Liquid Biopsy Analysis as a Tool for TKI-Based Treatment in Non-Small Cell Lung Cancer
Cells, 2022 The treatment of non-small cell lung cancer (NSCLC) has recently evolved with the introduction of targeted therapy based on the use of tyrosine kinase inhibitors (TKIs) in patients with certain gene alterations, including EGFR, ALK, ROS1, BRAF, and MET ...
Karolina Buszka +8 more
doaj +1 more source
Circulating tumor cells: Ready for translation? [PDF]
Journal of Experimental Medicine, 2020 Circulating tumor cells are tumor-derived pioneers responsible for the metastatic spread of cancer. Here, we outline recent discoveries, challenges, and future trends for circulating tumor cell investigations, arguing that the time is coming for translation of this work into clinical practice.
Nicola Aceto +3 more
openaire +4 more sources
The Potential for Circulating Tumor Cells in Pancreatic Cancer Management. [PDF]
, 2017 Pancreatic cancer is one the most lethal malignancies. Only a small proportion of patients with this disease benefit from surgery. Chemotherapy provides only a transient benefit.
Michael Pimienta +4 more
core +2 more sources
What information could the main actors of liquid biopsy provide? A representative case of non-small cell lung cancer (NSCLC) [PDF]
, 2018 In non-small cell lung cancer (NSCLC), there is a consensus regarding the use of liquid biopsy, generally, to detect "druggable" mutations and, in particular, to monitor tyrosine kinase inhibitor (TKI) treatments. However, whether circulating tumor cells
Manicone, M. +6 more
core +1 more source
Deterministic Separation of Cancer Cells from Blood at 10 mL/min [PDF]
, 2012 Circulating tumor cells (CTCs) and circulating clusters of cancer and stromal cells have been identified in the blood of patients with malignant cancer and can be used as a diagnostic for disease severity, assess the efficacy of different treatment ...
Amy Wu +5 more
core +3 more sources
Niche inheritance: a cooperative pathway to enhance cancer cell fitness though ecosystem engineering [PDF]
, 2014 Cancer cells can be described as an invasive species that is able to establish itself in a new environment. The concept of niche construction can be utilized to describe the process by which cancer cells terraform their environment, thereby engineering ...
Barar J +13 more
core +2 more sources