Results 71 to 80 of about 385,110 (187)

Permeability of the windows of the brain: feasibility of dynamic contrast-enhanced MRI of the circumventricular organs

, 2021
Background Circumventricular organs (CVOs) are small structures without a blood–brain barrier surrounding the brain ventricles that serve homeostasic functions and facilitate communication between the blood, cerebrospinal fluid and brain.
Alzheimer Center Limburg, de Jong, Joost J.A., Postma, Alida A., Jansen, Jaap F.A.; id_orcid, BioMedical Diagnostics, Orthopaedic Biomechanics, Maastricht University, Verheggen, Inge C.M., van Boxtel, Martin P.J., Verhey, Frans R.J., Backes, Walter H., Signal Processing Systems   +11 more
core   +1 more source

Diagnostic Challenges and Clinical Management of Area Postrema Syndrome: A Case Report on Persistent Nausea and Vomiting

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Area postrema syndrome (APS) is a rare neurological syndrome that presents a significant diagnostic challenge due to its nonspecific clinical manifestations, most commonly persistent nausea and vomiting, which frequently lead to initial misdiagnosis as a gastrointestinal disorder.
Andreea‐Gabriela Manole, D. Ion, Alexandra Bolocan, O. Andronic, D. N. Păduraru   +4 more
wiley   +1 more source

polifonia-project/organs-ontology: First release of the ORGANS ontology

, 2023
This repository contains the Organs ontology module of the Polifonia ontology network, which represents concepts and relationships to ...
Fiorela Ciroku
core   +1 more source

Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice

eLife, 2019
The circumventricular organs (CVOs) in the central nervous system (CNS) lack a vascular blood-brain barrier (BBB), creating communication sites for sensory or secretory neurons, involved in body homeostasis.
Fabienne Benz, Viraya Wichitnaowarat, Martin Lehmann, Raoul FV Germano, Diana Mihova, Jadranka Macas, Ralf H Adams, M Mark Taketo, Karl-Heinz Plate, Sylvaine Guérit, Benoit Vanhollebeke, Stefan Liebner   +11 more
doaj   +1 more source

Longitudinal Cognitive Evolution in Alcohol Use Disorder Patients: Role of Inflammation, Time of Abstinence and Apolipoprotein Profile

Addiction Biology, Volume 31, Issue 7, July 2026.
Thirty‐three AUD patients enrolled in an Alcohol Detoxification Program at Hospital Universitario 12 de Octubre (Madrid, Spain) and 34 healthy controls were followed for 12 months. AUD patients exhibited impaired general cognitive functioning, elevated plasma LPS and altered apolipoproteins (APOAI, APOAE, APOAJ, APOAM), which progressively normalized ...
Berta Escudero, Ricardo Olmos, Francisco Arias, Laura Orio   +3 more
wiley   +1 more source

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

Headache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1628-1643, July/August 2026.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone, Marcello Silvestro, Antonio Munafò, Marina Romozzi, Pierangelo Geppetti, Antonio Russo   +5 more
wiley   +1 more source

From sensory circumventricular organs to cerebral cortex: Neural pathways controlling thirst and hunger [PDF]

, 2019
Much progress has been made during the past 30 years with respect to elucidating the neural and endocrine pathways by which bodily needs for water and energy are brought to conscious awareness through the generation of thirst and hunger.
Brian J. Oldfield, Michael J. McKinley, Denton, DA, Derek A. Denton, Song T. Yao, McKinley, MJ, Ryan, PJ, Oldfield, BJ, Yao, ST, Philip J. Ryan, Aneta Stefanidis, Stefanidis, A   +11 more
core   +1 more source

Mapping of oxytocin‐ and arginine vasopressin‐expressing neurons with calbindin 1 or reelin in the male mouse brain

Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Calbindin 1 marks fluorogold‐positive magnocellular oxytocin neurons and a subset of magnocellular vasopressin neurons, whereas reelin marks a subset of fluorogold‐negative parvocellular oxytocin neurons. Abstract Oxytocin (OXT)‐ and arginine vasopressin (AVP)‐synthesizing neurons are traditionally classified into magnocellular and parvocellular types ...
Naranbat Nasanbuyan, Masahide Yoshida, Yuki Takayanagi, Keiichi Itoi, Tatsushi Onaka   +4 more
wiley   +1 more source

The Circumventricular Organs Form a Potential Neural Pathway for Lactate Sensitivity: Implications for Panic Disorder

, 1997
Patients with panic disorder experience panic attacks after intravenous sodium lactate infusions by an as yet unexplained mechanism. Lactate elicits a panic-like response in rats with chronic dysfunction of GABA neurotransmission in the dorsomedial ...
Stanley R. Keim, Shekhar, Anantha, Anantha Shekhar, Keim, Stanley R.   +3 more
core   +1 more source

Thirst sensation and oral dryness following alcohol intake

Japanese Dental Science Review, 2017
Substantial acute and chronic intakes of alcohol or ethanol (EtOH) severely influence oral sensations, such as thirst and oral dryness (dry mouth, xerostomia).
Kiyotoshi Inenaga, Kentaro Ono, Suzuro Hitomi, Ayu Kuroki, Izumi Ujihara   +4 more
doaj   +1 more source