Results 1 to 10 of about 55,491 (303)

Efficacy of Teduglutide in Pediatric Short Bowel Syndrome: Association with Citrulline Levels and Anatomical Location of Remnant Small Intestine [PDF]

open access: yesChildren
Background/Objectives: Short bowel syndrome (SBS) is the leading cause of pediatric intestinal failure. Plasma citrulline is considered a marker indicating an enterocyte volume and may help evaluate the response to teduglutide; however, this ...
Yudai Goto   +6 more
doaj   +2 more sources

Rootstock mediates transcriptional regulation of citrulline metabolism in grafted watermelon [PDF]

open access: yesBrazilian Journal of Biology, 2020
Citrulline is a non-essential amino acid, involved in key biological functions in plants and humans. Rootstocks have a major impact on citrulline accumulation in grafted watermelon. Information regarding rootstock induced changes in citrulline metabolism
A. Aslam   +4 more
doaj   +1 more source

Citrulline Accumulation Mechanism of Pediococcus acidilactici and Weissella confusa in Soy Sauce and the Effects of Phenolic Compound on Citrulline Accumulation

open access: yesFrontiers in Microbiology, 2021
Citrulline is one of the major precursors of ethyl carbamate in soy sauce, and the accumulation of citrulline is attributed to the metabolism of arginine by bacteria with the arginine deiminase (ADI) pathway.
Kai Zhou   +8 more
doaj   +1 more source

Oral administration of l-citrulline alters the vascular delivery of substances to rat skeletal muscles

open access: yesBiochemistry and Biophysics Reports, 2021
Vascular endothelial function deteriorates with age and disease, and the production of vasodilator factors like nitric oxide (NO) decreases. The free amino acid l-citrulline increases vasodilation and blood flow through increased NO production.
Sho Miyatake   +3 more
doaj   +1 more source

Impact of l‐citrulline on nitric oxide signaling and arginase activity in hypoxic human pulmonary artery endothelial cells

open access: yesPulmonary Circulation, 2023
Impaired nitric oxide (NO) signaling contributes to the development of pulmonary hypertension (PH). The l‐arginine precursor, l‐citrulline, improves NO signaling and has therapeutic potential in PH.
Matthew S. Douglass   +3 more
doaj   +1 more source

Bioavailability of Citrulline in Watermelon Flesh, Rind, and Skin Using a Human Intestinal Epithelial Caco-2 Cell Model

open access: yesApplied Sciences, 2023
Watermelon produces many byproducts (watermelon rind and skin) even though those components contain various bioactive compounds, including citrulline.
Inah Gu   +4 more
doaj   +1 more source

Modification of substrate specificity of l-arginine oxidase for detection of l-citrulline

open access: yesAMB Express, 2023
Enzymatic detection of citrulline, a potential biomarker for various diseases, is beneficial. However, determining citrulline levels requires expensive instrumental analyses and complicated colorimetric assays. Although l-amino acid oxidase/dehydrogenase
Kei Yamamoto   +4 more
doaj   +1 more source

Citrulline in the management of patients with urea cycle disorders

open access: yesOrphanet Journal of Rare Diseases, 2023
Background Treatment recommendations for urea cycle disorders (UCDs) include supplementation with amino acids involved in the urea cycle (arginine and/or citrulline, depending on the enzyme deficiency), to maximize ammonia excretion through the urea ...
Apolline Imbard   +10 more
doaj   +1 more source

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