Results 1 to 10 of about 51,040 (246)

Rootstock mediates transcriptional regulation of citrulline metabolism in grafted watermelon [PDF]

Brazilian Journal of Biology, 2020
Citrulline is a non-essential amino acid, involved in key biological functions in plants and humans. Rootstocks have a major impact on citrulline accumulation in grafted watermelon. Information regarding rootstock induced changes in citrulline metabolism
A. Aslam, Z. Shengjie, L. Xuqiang, H. Nan, L. Wenge   +4 more
doaj   +1 more source

Citrulline Accumulation Mechanism of Pediococcus acidilactici and Weissella confusa in Soy Sauce and the Effects of Phenolic Compound on Citrulline Accumulation

Frontiers in Microbiology, 2021
Citrulline is one of the major precursors of ethyl carbamate in soy sauce, and the accumulation of citrulline is attributed to the metabolism of arginine by bacteria with the arginine deiminase (ADI) pathway.
Kai Zhou, Kai Zhou, Kai Zhou, Xiao Zhang, Bingyong Li, Chaoqun Shen, Yuan-Ming Sun, Jianyuan Yang, Zhen-Lin Xu   +8 more
doaj   +1 more source

Oral administration of l-citrulline alters the vascular delivery of substances to rat skeletal muscles

Biochemistry and Biophysics Reports, 2021
Vascular endothelial function deteriorates with age and disease, and the production of vasodilator factors like nitric oxide (NO) decreases. The free amino acid l-citrulline increases vasodilation and blood flow through increased NO production.
Sho Miyatake, Kazuo Hino, Goro Ebisu, Satoshi Fujita   +3 more
doaj   +1 more source

Impact of l‐citrulline on nitric oxide signaling and arginase activity in hypoxic human pulmonary artery endothelial cells

Pulmonary Circulation, 2023
Impaired nitric oxide (NO) signaling contributes to the development of pulmonary hypertension (PH). The l‐arginine precursor, l‐citrulline, improves NO signaling and has therapeutic potential in PH.
Matthew S. Douglass, Mark R. Kaplowitz, Yongmei Zhang, Candice D. Fike   +3 more
doaj   +1 more source

Bioavailability of Citrulline in Watermelon Flesh, Rind, and Skin Using a Human Intestinal Epithelial Caco-2 Cell Model

Applied Sciences, 2023
Watermelon produces many byproducts (watermelon rind and skin) even though those components contain various bioactive compounds, including citrulline.
Inah Gu, Olugbenga Balogun, Cindi Brownmiller, Hye Won Kang, Sun-Ok Lee   +4 more
doaj   +1 more source

Modification of substrate specificity of l-arginine oxidase for detection of l-citrulline

AMB Express, 2023
Enzymatic detection of citrulline, a potential biomarker for various diseases, is beneficial. However, determining citrulline levels requires expensive instrumental analyses and complicated colorimetric assays. Although l-amino acid oxidase/dehydrogenase
Kei Yamamoto, Yosuke Masakari, Yasuko Araki, Atsushi Ichiyanagi, Kotaro Ito   +4 more
doaj   +1 more source

Citrulline in the management of patients with urea cycle disorders

Orphanet Journal of Rare Diseases, 2023
Background Treatment recommendations for urea cycle disorders (UCDs) include supplementation with amino acids involved in the urea cycle (arginine and/or citrulline, depending on the enzyme deficiency), to maximize ammonia excretion through the urea ...
Apolline Imbard, Juliette Bouchereau, Jean-Baptiste Arnoux, Anaïs Brassier, Manuel Schiff, Claire-Marine Bérat, Clément Pontoizeau, Jean-François Benoist, Constant Josse, François Montestruc, Pascale de Lonlay   +10 more
doaj   +1 more source

Enhancement of fracture healing after citrulline supplementation in mice [PDF]

European Cells & Materials, 2020
Around 10 % of long bone fractures show inadequate bone healing resulting in non-union development. A deregulated arginine-citrulline-nitric oxide metabolism caused by a poor nutritional status of the patients is a risk factor for non-unions ...
DM Meesters, PFW Hannemann,, HMH van Eijk, VTJ Schriebl, PRG Brink, M Poeze, KAP Wijnands   +6 more
doaj   +1 more source

L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

Pulmonary Circulation, 2021
The L-arginine precursor, L-citrulline, re-couples endothelial nitric oxide synthase, increases nitric oxide production, and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
Matthew S. Douglass, Yongmei Zhang, Mark R. Kaplowitz, Candice D. Fike   +3 more
doaj   +1 more source

Evaluation of the Utility of Amino Acid Citrulline as a Surrogate Metabolomic Biomarker for the Diagnosis of Celiac Disease

Nutrition and Metabolic Insights, 2021
Introduction: Citrulline is regarded as a biomarker for celiac disease (CD). Its utility for assessment and evaluation of additive predictive value for latent, potential CD and first degree relatives (FDRs) needs exploration.
Avinash Lomash, Anupa Prasad, Raghvendra Singh, Somesh Kumar, Rishi Gupta, Dhwani Dholakia, Praveen Kumar, Vineeta V Batra, Amarender S Puri, Seema Kapoor   +9 more
doaj   +1 more source