Results 41 to 50 of about 34,606 (279)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Circulating concentrations of citrulline, neopterin, kynurenine, and tryptophan during chemoradiation in patients with cervical carcinoma

Pteridines, 2021
The aim of this study was to investigate the changes in circulating concentrations of citrulline, neopterin, kynurenine, and tryptophan during the course of chemoradiation in patients with cervical cancer.
Pospíšková Markéta, Strouhal Ondřej, Hlídková Eva, Vlachová Zuzana, Melichar Bohuslav, Doležel Martin   +5 more
doaj   +1 more source

Investigation of endocrine response of thyroid and intestinal and adipose tissues due to the addition of Moringa oleifera essential oil in diet for quails exposed to heat stress

Revista Brasileira de Zootecnia, 2023
In this study, we aimed to determine the effect of Moringa oleifera essential oil (MOEO) supplementation to rations of Japanese quail ( Coturnix coturnix japonica ) grown under heat stress (HS) on some adipokine (visfatin, adiponectin, and chemerin ...
Bülent Bayraktar, Emre Tekce, Sevil Bayraktar, Gülbahar Böyük, Çiğdem Takma, Vecihi Aksakal, Murat Genç, Hacer Kaya, Ufuk Ülker, Ahmet Burak Gürbüz   +9 more
doaj   +1 more source

Determination of Citrulline in Plasma

Clinical Chemistry, 1960
Abstract The Archibald method for the determination of plasma citrulline has been modified to eliminate the dialysis step in order to separate citrulline from plasma proteins. Instead these are precipitated with picric acid and the picrate ion removed by passage through an anion exchange column.
M P, MOCKLER, L R, MENEBROKER, F L, HUMOLLER, A J, BARAK   +3 more
openaire   +2 more sources

Seeing Citrulline: Development of a Phenylglyoxal-Based Probe To Visualize Protein Citrullination [PDF]

Journal of the American Chemical Society, 2012
Protein arginine deiminases (PADs) catalyze the hydrolysis of peptidyl arginine to form peptidyl citrulline. Abnormally high PAD activity is observed in a host of human diseases, but the exact role of protein citrullination in these diseases and the identities of specific citrullinated disease biomarkers remain unknown, largely because of the lack of ...
Bicker, Kevin L., Subramanian, Venkataraman, Chumanevich, Alexander A., Hofseth, Lorne J., Thompson, Paul R   +4 more
openaire   +3 more sources

Desenvolvimento de metodologia analítica por cromatografia líquida de alta eficiência e eletroforese capilar para análise de citrulina em matrizes biológicas: Ana Claudia Vieira; orientador, Flavio Henrique Reginatto. [PDF]

, 2014
A intensa busca por novos biomarcadores de doenças com intuito de melhorar o diagnóstico e acompanhar a evolução da doença tem feito os pesquisadores reavaliar compostos antes ignorados, como a citrulina.
Vieira, Ana Claudia
core  

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

l-Citrulline ameliorates cerebral blood flow during cortical spreading depression in rats: Involvement of nitric oxide- and prostanoids-mediated pathway

Journal of Pharmacological Sciences, 2017
l-Citrulline is a potent precursor of l-arginine, and exerts beneficial effect on cardiovascular system via nitric oxide (NO) production. Migraine is one of the most popular neurovascular disorder, and imbalance of cerebral blood flow (CBF) observed in ...
Yuki Kurauchi, Koichi Mokudai, Asami Mori, Kenji Sakamoto, Tsutomu Nakahara, Masahiko Morita, Ayako Kamimura, Kunio Ishii   +7 more
doaj   +1 more source

Manipulation of citrulline availability in humans

, 2007
International audienceTo determine whether circulating citrulline can be manipulated in vivo in humans, and, if so, whether citrulline availability affects the levels of related amino acids, nitric oxide, urinary citrulline, and urea nitrogen, 10 healthy
Des Robert, Clotilde, Robins, Alexander, Rougé, Carole, Darmaun, Dominique, Le Bacquer, Olivier, Volteau, Christelle, de la Cochetière, Marie-France   +6 more
core   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source