Results 31 to 40 of about 34,707 (264)

Protective effect of citrulline on the intestinal

open access: yesPakistan Journal of Pharmaceutical Sciences, 2023
Excessive inflammation caused by sepsis can disrupt gut mucosal barrier and aggravate sepsis. The purpose of the study was to confirm whether citrulline can protect the intestinal mucosal barrier during sepsis.
Rui Xu, Lifang Qiu
doaj   +1 more source

Plasma citrulline levels. [PDF]

open access: yes, 2022
Plasma citrulline levels were measured in patients with normal zinc levels (black bars) and patients with zinc deficiency (white bars) at admission and day+7.
Suradej Hongeng (285857)   +7 more
core   +1 more source

Autophagy, citrullination and cancer [PDF]

open access: yesAutophagy, 2016
A cell needs to maintain a balance between biosynthesis and degradation of cellular components to maintain homeostasis. There are 2 pathways, the proteasome, which degrades short-lived proteins, and the autophagy/lysosomal pathway, which degrades long-lived proteins and organelles. Both of these pathways are also involved in antigen presentation or the
Lindy G, Durrant   +2 more
openaire   +2 more sources

l-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo

open access: yesJournal of Pharmacological Sciences, 2015
l-Citrulline is an effective precursor of l-arginine produced by the l-citrulline/l-arginine cycle, and it exerts beneficial effects on the cardiovascular system by supporting enhanced nitric oxide (NO) production.
Asami Mori   +5 more
doaj   +1 more source

Rheumatoid arthritis and citrullination [PDF]

open access: yesCurrent Opinion in Rheumatology, 2018
Purpose of reviewDysregulated citrullination is a key element that drives the production and maintenance of antibodies to citrullinated proteins, a hallmark in rheumatoid arthritis (RA). This article reviews recent literature on the origin of citrullinated antigens in RA.Recent findingsThe study of synovial fluid from patients with RA has provided ...
Erika, Darrah, Felipe, Andrade
openaire   +2 more sources

The effect of citrulline and citrulline malate supplementation on selected physiological indicators - review study [PDF]

open access: yes, 2021
Title: The effect of citrulline and citrulline malate supplementation on selected physiological indicators - review study. Objectives: Systematic findings overview of the effect of citrulline and citrulline malate on healthy individual's locomotor system
Richter, Michael
core  

L-Citrulline Protects Skeletal Muscle Cells from Cachectic Stimuli through an iNOS-Dependent Mechanism. [PDF]

open access: yesPLoS ONE, 2015
Dietary L-citrulline is thought to modulate muscle protein turnover by increasing L-arginine availability. To date, the direct effects of increased L-citrulline concentrations in muscle have been completely neglected. Therefore, we determined the role of
Daniel J Ham   +6 more
doaj   +1 more source

Citrullination in Cancer [PDF]

open access: yesCancer Research, 2019
Abstract Posttranslational modifications of proteins have been implicated in pathogenesis of numerous diseases. Arginine deimination (also known as citrullination) has a principal role in progression of rheumatoid arthritis through generation of autoantibodies and exacerbation of the inflammatory response.
openaire   +2 more sources

Citrulline and intestinal fatty acid-binding protein as biomarkers for gastrointestinal dysfunction in the critically ill [PDF]

open access: yes, 2019
Currently there is no reliable tool available to monitor gastrointestinal function in the critically ill. Biomarkers are therefore of great interest in this field as the lack of monitoring tools impedes any interventional studies.
Blaser, Annika   +9 more
core   +1 more source

Sodium-coupled neutral amino acid transporter 1 (SNAT1) modulates L-citrulline transport and nitric oxide (NO) signaling in piglet pulmonary arterial endothelial cells. [PDF]

open access: yesPLoS ONE, 2014
There is evidence that impairments in nitric oxide (NO) signaling contribute to chronic hypoxia-induced pulmonary hypertension. The L-arginine-NO precursor, L-citrulline, has been shown to ameliorate pulmonary hypertension.
Anna Dikalova   +5 more
doaj   +1 more source

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