Results 11 to 20 of about 37,088 (271)

Chemoreactomic analysis of citrulline malate molecules

open access: yesНеврология, нейропсихиатрия, психосоматика, 2017
Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
I. Yu. Torshin   +4 more
doaj   +2 more sources

Citrulline in the management of patients with urea cycle disorders

open access: yesOrphanet Journal of Rare Diseases, 2023
Background Treatment recommendations for urea cycle disorders (UCDs) include supplementation with amino acids involved in the urea cycle (arginine and/or citrulline, depending on the enzyme deficiency), to maximize ammonia excretion through the urea ...
Apolline Imbard   +10 more
doaj   +2 more sources

Binding Ability Studies of Arginine, Citrulline, N-Acetyl Citrulline and Thiocitrulline with SARS Cov-2 Main Protease Using Molecular Docking Studies [PDF]

open access: yes, 2020
To Editor in Chief Chemarxiv Respected Sir/Madam Subject: submission of preprint of an article to ChemRxiv on molecular docking studies of arginine and its structural analogues on COV-19 for publication.
Ramesh, Thimmasandra Narayan
core   +1 more source

Citrullination and Autophagy [PDF]

open access: yes, 2017
During evolution, the eukaryotic cells develop different processes in order to adapt themselves to environmental changes, as well as to die or to survive. These processes include apoptosis, NETosis, and autophagy: citrullination is implicated in all of these physiological mechanisms.
Guido Valesini   +5 more
openaire   +1 more source

Functional Relevance of Citrulline in the Vegetative Tissues of Watermelon During Abiotic Stresses

open access: yesFrontiers in Plant Science, 2020
A non-protein amino acid, citrulline, is a compatible solute involved in the maintenance of cellular osmolarity during abiotic stresses. Despite its significance, a coherent model indicating the role of citrulline during stress conditions has not yet ...
Qiushuo Song   +5 more
doaj   +1 more source

L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

open access: yesPulmonary Circulation, 2021
The L-arginine precursor, L-citrulline, re-couples endothelial nitric oxide synthase, increases nitric oxide production, and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
Matthew S. Douglass   +3 more
doaj   +1 more source

Evaluation of the Utility of Amino Acid Citrulline as a Surrogate Metabolomic Biomarker for the Diagnosis of Celiac Disease

open access: yesNutrition and Metabolic Insights, 2021
Introduction: Citrulline is regarded as a biomarker for celiac disease (CD). Its utility for assessment and evaluation of additive predictive value for latent, potential CD and first degree relatives (FDRs) needs exploration.
Avinash Lomash   +9 more
doaj   +1 more source

Protective effect of citrulline on the intestinal

open access: yesPakistan Journal of Pharmaceutical Sciences, 2023
Excessive inflammation caused by sepsis can disrupt gut mucosal barrier and aggravate sepsis. The purpose of the study was to confirm whether citrulline can protect the intestinal mucosal barrier during sepsis.
Rui Xu, Lifang Qiu
doaj   +1 more source

Citrullination in Cancer [PDF]

open access: yesCancer Research, 2019
Abstract Posttranslational modifications of proteins have been implicated in pathogenesis of numerous diseases. Arginine deimination (also known as citrullination) has a principal role in progression of rheumatoid arthritis through generation of autoantibodies and exacerbation of the inflammatory response.
openaire   +2 more sources

Rheumatoid arthritis and citrullination [PDF]

open access: yesCurrent Opinion in Rheumatology, 2018
Purpose of reviewDysregulated citrullination is a key element that drives the production and maintenance of antibodies to citrullinated proteins, a hallmark in rheumatoid arthritis (RA). This article reviews recent literature on the origin of citrullinated antigens in RA.Recent findingsThe study of synovial fluid from patients with RA has provided ...
Erika, Darrah, Felipe, Andrade
openaire   +2 more sources

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