Results 21 to 30 of about 51,040 (246)
Journal of Pharmacological Sciences, 2015 l-Citrulline is an effective precursor of l-arginine produced by the l-citrulline/l-arginine cycle, and it exerts beneficial effects on the cardiovascular system by supporting enhanced nitric oxide (NO) production.
Asami Mori +5 more
doaj +1 more source
Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? [PDF]
, 2016 Background: Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis.
Bosch, Guido +13 more
core +2 more sources
Chemoreactomic analysis of citrulline malate molecules
Неврология, нейропсихиатрия, психосоматика, 2017 Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
I. Yu. Torshin +4 more
doaj +1 more source
Citrullination and Autophagy [PDF]
, 2017 During evolution, the eukaryotic cells develop different processes in order to adapt themselves to environmental changes, as well as to die or to survive. These processes include apoptosis, NETosis, and autophagy: citrullination is implicated in all of these physiological mechanisms.
Guido Valesini +5 more
openaire +1 more source
Autophagy, citrullination and cancer [PDF]
Autophagy, 2016 A cell needs to maintain a balance between biosynthesis and degradation of cellular components to maintain homeostasis. There are 2 pathways, the proteasome, which degrades short-lived proteins, and the autophagy/lysosomal pathway, which degrades long-lived proteins and organelles. Both of these pathways are also involved in antigen presentation or the
Lindy G, Durrant +2 more
openaire +2 more sources
Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome. [PDF]
PLoS ONE, 2013 In humans, plasma amino acid concentrations of branched-chain amino acids (BCAA) and aromatic amino acids (AAA) increase in states of obesity, insulin resistance and diabetes.
Manuela Sailer +8 more
doaj +1 more source
Antioxidants, 2022 Intermittent hypoxia (IH) is a landmark of obstructive sleep apnea (OSA) at the core of the cardiovascular consequences of OSA. IH triggers oxidative stress, a major underlying mechanism for elevated blood pressure (BP) and increased infarct size.
Bilgehan Ozcan +10 more
doaj +1 more source
Citrulline as a marker of intestinal function and absorption in clinical settings: A systematic review and meta-analysis [PDF]
, 2017 Background: Citrulline has been described as a marker of intestinal function or absorption but evidence varies according to clinical settings. Objective: The objective of this article is to examine the evidence of plasma citrulline as a marker of ...
Blasco Alonso J +11 more
core +3 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemia. [PDF]
PLoS ONE, 2012 BACKGROUND: Impaired microcirculation during endotoxemia correlates with a disturbed arginine-nitric oxide (NO) metabolism and is associated with deteriorating organ function.
Karolina A P Wijnands +6 more
doaj +1 more source