Results 31 to 40 of about 51,040 (246)
In this study, we aimed to determine the effect of Moringa oleifera essential oil (MOEO) supplementation to rations of Japanese quail ( Coturnix coturnix japonica ) grown under heat stress (HS) on some adipokine (visfatin, adiponectin, and chemerin ...
Bülent Bayraktar +9 more
doaj +1 more source
Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients [PDF]
Antibodies against citrullinated proteins are highly specific for rheumatoid arthritis (RA) and are currently used as a diagnostic marker. In this study, we wanted to quantify the numbers of T cells that react to a wide range of citrullinated proteins in
De Ceuleneer, Marlies +5 more
core +1 more source
Citrullination in Cancer [PDF]
Abstract Posttranslational modifications of proteins have been implicated in pathogenesis of numerous diseases. Arginine deimination (also known as citrullination) has a principal role in progression of rheumatoid arthritis through generation of autoantibodies and exacerbation of the inflammatory response.
openaire +2 more sources
Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]
In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
core +1 more source
Clinical and model studies indicate that low nitric oxide (NO) bioavailability due in part to profound hypoargininemia contributes to cerebral malaria (CM) pathogenesis.
Irene Gramaglia +7 more
doaj +1 more source
Immune recognition of citrullinated epitopes [PDF]
SummaryConversion of arginine into citrulline is a post‐translational modification that is observed in normal physiological processes. However, abnormal citrullination can provoke autoimmunity by generating altered self‐epitopes that are specifically targeted by autoantibodies and T cells.
Hai, Nguyen, Eddie A, James
openaire +2 more sources
Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer. [PDF]
BackgroundPancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have ...
Bold, Richard J +3 more
core +2 more sources
Background Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a consequence. L-arginine can also be synthesized by L-citrulline recycling.
Sopi Ramadan B +7 more
doaj +1 more source
Background: Reperfusion or reopening of occluded vessels is the gold standard to terminate ischemia. However, early functional recovery after reperfusion is often low requiring inotropic intervention.
Marc Heidorn +4 more
doaj +1 more source
Background: Citrulline is one of the non-essential amino acids that is thought to improve exercise performance and reduce post-exercise muscle soreness. We conducted a systematic review and meta-analysis to determine the effect of citrulline supplements ...
Hye Chang Rhim +3 more
doaj +1 more source

