Results 31 to 40 of about 51,040 (246)

Investigation of endocrine response of thyroid and intestinal and adipose tissues due to the addition of Moringa oleifera essential oil in diet for quails exposed to heat stress

open access: yesRevista Brasileira de Zootecnia, 2023
In this study, we aimed to determine the effect of Moringa oleifera essential oil (MOEO) supplementation to rations of Japanese quail ( Coturnix coturnix japonica ) grown under heat stress (HS) on some adipokine (visfatin, adiponectin, and chemerin ...
Bülent Bayraktar   +9 more
doaj   +1 more source

Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients [PDF]

open access: yes, 2013
Antibodies against citrullinated proteins are highly specific for rheumatoid arthritis (RA) and are currently used as a diagnostic marker. In this study, we wanted to quantify the numbers of T cells that react to a wide range of citrullinated proteins in
De Ceuleneer, Marlies   +5 more
core   +1 more source

Citrullination in Cancer [PDF]

open access: yesCancer Research, 2019
Abstract Posttranslational modifications of proteins have been implicated in pathogenesis of numerous diseases. Arginine deimination (also known as citrullination) has a principal role in progression of rheumatoid arthritis through generation of autoantibodies and exacerbation of the inflammatory response.
openaire   +2 more sources

Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]

open access: yes, 2017
In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
core   +1 more source

Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak.

open access: yesPLoS ONE, 2019
Clinical and model studies indicate that low nitric oxide (NO) bioavailability due in part to profound hypoargininemia contributes to cerebral malaria (CM) pathogenesis.
Irene Gramaglia   +7 more
doaj   +1 more source

Immune recognition of citrullinated epitopes [PDF]

open access: yesImmunology, 2016
SummaryConversion of arginine into citrulline is a post‐translational modification that is observed in normal physiological processes. However, abnormal citrullination can provoke autoimmunity by generating altered self‐epitopes that are specifically targeted by autoantibodies and T cells.
Hai, Nguyen, Eddie A, James
openaire   +2 more sources

Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer. [PDF]

open access: yes, 2014
BackgroundPancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have ...
Bold, Richard J   +3 more
core   +2 more sources

L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia

open access: yesRespiratory Research, 2012
Background Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a consequence. L-arginine can also be synthesized by L-citrulline recycling.
Sopi Ramadan B   +7 more
doaj   +1 more source

Citrulline Improves Early Post-Ischemic Recovery or Rat Hearts In Vitro by Shifting Arginine Metabolism From Polyamine to Nitric Oxide Formation

open access: yesClinical Medicine Insights: Cardiology, 2018
Background: Reperfusion or reopening of occluded vessels is the gold standard to terminate ischemia. However, early functional recovery after reperfusion is often low requiring inotropic intervention.
Marc Heidorn   +4 more
doaj   +1 more source

Effect of citrulline on post-exercise rating of perceived exertion, muscle soreness, and blood lactate levels: A systematic review and meta-analysis

open access: yesJournal of Sport and Health Science, 2020
Background: Citrulline is one of the non-essential amino acids that is thought to improve exercise performance and reduce post-exercise muscle soreness. We conducted a systematic review and meta-analysis to determine the effect of citrulline supplements ...
Hye Chang Rhim   +3 more
doaj   +1 more source

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