Results 41 to 50 of about 55,491 (303)

Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer. [PDF]

, 2014
BackgroundPancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have ...
Bold, Richard J, Daylami, Rouzbeh, Muilenburg, Diego J, Virudachalam, Subbulakshmi   +3 more
core   +2 more sources

L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia

Respiratory Research, 2012
Background Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a consequence. L-arginine can also be synthesized by L-citrulline recycling.
Sopi Ramadan B, Zaidi Syed IA, Mladenov Mitko, Sahiti Hazbije, Istrefi Zahide, Gjorgoski Icko, Lajçi Azem, Jakupaj Muharrem   +7 more
doaj   +1 more source

Citrulline Improves Early Post-Ischemic Recovery or Rat Hearts In Vitro by Shifting Arginine Metabolism From Polyamine to Nitric Oxide Formation

Clinical Medicine Insights: Cardiology, 2018
Background: Reperfusion or reopening of occluded vessels is the gold standard to terminate ischemia. However, early functional recovery after reperfusion is often low requiring inotropic intervention.
Marc Heidorn, Tim Frodermann, Andreas Böning, Rolf Schreckenberg, Klaus-Dieter Schlüter   +4 more
doaj   +1 more source

Effect of citrulline on post-exercise rating of perceived exertion, muscle soreness, and blood lactate levels: A systematic review and meta-analysis

Journal of Sport and Health Science, 2020
Background: Citrulline is one of the non-essential amino acids that is thought to improve exercise performance and reduce post-exercise muscle soreness. We conducted a systematic review and meta-analysis to determine the effect of citrulline supplements ...
Hye Chang Rhim, Sung Jong Kim, Jewel Park, Ki-Mo Jang   +3 more
doaj   +1 more source

Functional Quality and Radical Scavenging Activity of Selected Watermelon (Citrullus lanatus (Thunb.) Mansfeld) Genotypes as Affected by Early and Full Cropping Seasons

Plants, 2023
Growing conditions and seasonal fluctuations are critical factors affecting fruit and vegetable nutritional quality. The effects of two partially overlapping cropping seasons, early (ECS; January–May) and full (FCS; March–July), on the main carpometric ...
Imen Tlili, Riadh Ilahy, Leila Romdhane, Thouraya R’him, Hatem Ben Mohamed, Hatem Zgallai, Zouhair Rached, Muhammad Azam, Imen Henane, Mohamed Najib Saïdi, Zoltàn Pék, Hussein G. Daood, Lajos Helyes, Chafik Hdider, Marcello Salvatore Lenucci   +14 more
doaj   +1 more source

Watermelon Juice: Potential Functional Drink for Sore Muscle Relief in Athletes [PDF]

, 2013
L-Citrulline is an excellent candidate to reduce muscle soreness, and watermelon is a fruit rich in this amino acid. This study investigated the potential of watermelon juice as a functional drink for athletes.
Aguayo, Encarna, Alacid, Fernando, Carrasco, María, Martínez, Ignacio, Tarazona Díaz, Martha P.   +4 more
core   +2 more sources

Effects of citrulline on endurance performance in young healthy adults: a systematic review and meta-analysis

Journal of the International Society of Sports Nutrition, 2023
Background Citrulline is a popular dietary supplement, primarily thought to exert ergogenic effects on exercise performance through the enhancement of nitric oxide (NO) synthesis and ammonia buffering.
Callum S. Harnden, JOSEPH Agu, TOM Gascoyne   +2 more
doaj   +1 more source

Plasma Amino Acids in Horses Suffering from Pituitary Pars Intermedia Dysfunction

Animals, 2022
Pituitary pars intermedia dysfunction is one of the most common diseases of aged horses and ponies. In Parkinson’s disease, which is, similar to PPID, a disease that involves oxidative damage to dopaminergic pathways but with different clinical signs ...
Sabita Diana Stoeckle, Detlef Timmermann, Roswitha Merle, Heidrun Gehlen   +3 more
doaj   +1 more source

¹³C NMR metabolomics: applications at natural abundance. [PDF]

, 2014
(13)C NMR has many advantages for a metabolomics study, including a large spectral dispersion, narrow singlets at natural abundance, and a direct measure of the backbone structures of metabolites.
Clendinen, Chaevien, Edison, Arthur, Hahn, Daniel, Lee-McMullen, Brittany, Stupp, Gregory, Vandenborne, Krista, Walter, Glenn, Williams, Caroline   +7 more
core   +3 more sources

Ann Rheum Dis [PDF]

, 2011
Objective This study was conducted with sera from patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and arthritis and lupus-like disease animal models to identify innate immune system-dependent and -independent ...
Burmester, G., Häupl, T., Konthur, Z., Marklein, B., Shlomchik, M., Skriner, K.   +5 more
core   +2 more sources