Results 71 to 80 of about 55,491 (303)
Methylation-dependent PAD2 upregulation in multiple sclerosis peripheral blood [PDF]
, 2012 Background: Peptidylarginine deiminase 2 (PAD2) and peptidylarginine deiminase 4 (PAD4) are two members of PAD family which are over-expressed in the multiple sclerosis (MS) brain.
ANNIBALI, Viviana +9 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Anticitrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among patients with RA, including for motif‐containing epitopes in important self‐antigens like ...
S. Janna Bashar +4 more
wiley +1 more source
The preparation of citrulline by hydrolysis of arginine [PDF]
, 1938 The theoretical hydrolysis of arginine to citrulline in vitro has been accomplished and discussed. The details for rapidly and conveniently preparing a 65 gm.
Fox, Sidney W.
core
, 2018 Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) may be directly pathogenic.
Amara, Khaled +17 more
core +2 more sources
Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers : implications for autoimmunity in rheumatoid arthritis [PDF]
, 2015 Introduction: Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic.
Bracke, Ken +8 more
core +2 more sources
Effect of L-citrulline, L-leucine, and multicomponent exercises on body compositions, physical activity, and amino acid concentrations in older Japanese women with low body mass index: A randomized double-blind placebo-controlled study [PDF]
, 2021 Mijin Kim, Hiroko Isoda, Tomohiro Okura
openalex +1 more source
ChemistryEurope, EarlyView.Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn +6 more
wiley +1 more source
l-Citrulline Supplementation-Increased Skeletal Muscle PGC-1α Expression Is Associated with Exercise Performance and Increased Skeletal Muscle Weight [PDF]
, 2018 1 Scopel‐citrulline has recently been reported as a more effective supplement for promoting intracellular nitric oxide (NO) production compared to l‐arginine.
Isoda Hiroko +3 more
core +2 more sources
Biosynthesis of Citrulline in Plants [PDF]
Nature, 1961 IN 1930 citrulline was discovered in water-melons1. Later it was shown to be an important participant in the Krebs and Henseleit ornithine cycle in animals and micro-organisms. In recent years several laboratories have worked on the ornithine cycle in plants.
openaire +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka +12 more
wiley +1 more source