Results 81 to 90 of about 37,088 (271)

Citrulline metabolism in normal and citrullinemic human lymphocyte lines [PDF]

, 1975
Citrullinemia is one of the five aminoacidurias associated with the Krebs-Henseleit urea cycle. A long-term lymphocyte line (UM-21) derived from a patient with this disease and nine of ten clones of this line were found to have no activity for the enzyme
Arthur D. Bloom, Spector, Elaine B., Lockridge, Oksana, Oksana Lockridge, Elaine B. Spector, Bloom, Arthur D.   +5 more
core   +1 more source

Homocitrullinated Peptides Drive Pro‐Inflammatory T Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova, Jaspreet Kaur, Gabrielle Buckley, S. M. Mansour Haeryfar, Lisa Cameron, Ewa Cairns, Lillian Barra   +6 more
wiley   +1 more source

Correlation of plasma metabolites with glucose and lipid fluxes in human insulin resistance

Obesity Science & Practice, 2020
Summary Objective Insulin resistance develops prior to the onset of overt type 2 diabetes, making its early detection vital. Direct accurate evaluation is currently only possible with complex examinations like the stable isotope‐based hyperinsulinemic ...
Annick V. Hartstra, Pieter F. deGroot, Diogo Mendes Bastos, Evgeni Levin, Mireille J. Serlie, Maarten R. Soeters, Ceyda T. Pekmez, Lars O. Dragsted, Mariette T. Ackermans, Albert K. Groen, Max Nieuwdorp   +10 more
doaj   +1 more source

DataSheet_1_Characterization of Monoclonal Antibodies Recognizing Citrulline-Modified Residues.pdf

, 2022
BackgroundCitrullination is a post-translational protein modification linked to the occurrence and development of a variety of diseases. The detection of citrullinated proteins is predominately based on antibody detection although currently available ...
Chenxi Deng (12227234), Cao Li (740471), Yaqiong Chen (5395739), Lin Weng (19882), Jinlu Jiang (12227240), Juan Chen (61123), Jinxiu Xuan (12227237), Wei Liu (20030), Shengxiang Ge (363544), Yuan Ma (189824)   +9 more
core   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility

Cell Reports, 2018
Summary: Recent proteome analyses have provided a comprehensive overview of various posttranslational modifications (PTMs); however, PTMs involving protein citrullination remain unclear. We performed a proteomic analysis of citrullinated proteins, and we
Chizu Tanikawa, Koji Ueda, Akari Suzuki, Aritoshi Iida, Ryoichi Nakamura, Naoki Atsuta, Genki Tohnai, Gen Sobue, Naomi Saichi, Yukihide Momozawa, Yoichiro Kamatani, Michiaki Kubo, Kazuhiko Yamamoto, Yusuke Nakamura, Koichi Matsuda   +14 more
doaj   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source

Intravenous citrulline generation test to assess intestinal function in intensive care unit patients

, 2017
Job HC Peters,1 Nicolette J Wierdsma,2,3 Albertus Beishuizen,4,5 Tom Teerlink,6 Ad A van Bodegraven,3,7 1Department of Gastroenterology and Hepatology, Red Cross Hospital, Beverwijk, 2Department of Nutrition and Dietetics, VU University Medical Center ...
Teerlink T, van Bodegraven AA, Peters JH, Wierdsma NJ, Beishuizen A   +4 more
core  

Amino Acid and Biogenic Amine Profiles in Sausages Reformulated With Processed, Fermented Oyster Mushrooms

ChemFoodChem, EarlyView.
This research showed that sausage reformulation preserves high essential amino acid and branched‐chain amino acid content, as well as increasing free amino acids (FAA) related to umami flavor and health‐promoting components such as GABA in the products.
Albert Gashi, György Kenesei, Meltem Boylu Kovács, Zsuzsanna Mednyánszky, Livia Simon Sarkadi   +4 more
wiley   +1 more source

Citrulline as a nutraceutical protects against eCM.

, 2019
Groups (n = 5) of mice were injected i.v. with PbA and then injected twice daily ip with citrulline (nutraceutical) or saline. (A): survival, (B): parasitemia (mean % ± stderr) timecourse, and (C): clinical scores of citrulline- and saline-injected mice ...
Henri C. van der Heyde (6439625), Irene Gramaglia (6439613), Yu-Sun Chang (144676), Monique F. Stins (6439622), Wilson Caparros-Wanderley (6439619), Joyce Velez (6439616), Valery Combes (104149), Georges Grau (5206004)   +7 more
core   +1 more source