Results 61 to 70 of about 409,684 (298)

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Effect of unsaturated C18 fatty acids (oleic, linoleic and α-linolenic acids) on ruminal fermentation and production of fatty acids isomers in artificial rumen

open access: yesVeterinární Medicína, 2007
The objective of this study was to examine the effect of oleic (OA), linoleic (LA) and α-linolenic (ALA) acid used as supplements (3.5% wt/wt) to a diet containing 80% lucerne and 20% barley on rumen fermentation and lipid metabolism in an artificial ...
D. Jalc   +3 more
doaj   +1 more source

Beyond Reporting: The Integration of Climate Change and Biodiversity Into Business Strategies and Governance Structures of Swedish Firms and Financial Institutions

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This paper analyses how large Swedish firms and financial institutions integrate climate change and biodiversity into their business strategies and governance structures. Using unique 2022 and 2023 survey data and logistic probability models, we examine how internal and external factors shape early responses to the EU Taxonomy and the CSRD ...
Fredrik N. G. Andersson   +1 more
wiley   +1 more source

Cord-lamina angle and foraminal diameter as key predictors of C5 palsy after anterior cervical decompression and fusion surgery

open access: yesOpen Medicine
C5 nerve root palsy (C5P) is a rare but documented complication after cervical decompression surgery. Despite multiple proposed mechanisms, research on risk factors for C5P after anterior cervical discectomy and fusion (ACDF) remains insufficient.
Zhou Wenchao   +8 more
doaj   +1 more source

Long term conjugated linoleic acid supplementation modestly improved growth performance but induced testicular tissue apoptosis and reduced sperm quality in male rabbit.

open access: yesPLoS ONE, 2020
Conjugated linoleic acid (CLA) is known for its multiple benefits including improvement of growth, increasing lean mass, and anti-carcinogenic effects.
A M Abdelatty   +10 more
doaj   +1 more source

Aroma-active secondary oxidation products of butter [PDF]

open access: yes, 2007
Butter contains vitamins, minerals and unsaturated lipids, such as polyunsaturated fatty acids (PUFA) and conjugated linoleic acids (CLAs). However the oxidative stability and consequently the shelf-life of milk products are inversely correlated with ...
Escher, Felix   +3 more
core  

Dietary conjugated linoleic acid differentially alters fatty acid composition and increases conjugated linoleic acid content in porcine adipose tissue [PDF]

open access: yes, 2003
Conjugated linoleic acids (CLA) have been shown to decrease body fat content in pigs. It is possible that feeding pigs diets rich in CLA may increase carcass lipid CLA to levels that could provide health benefits when included as a part of a healthy diet.
de Deckere   +7 more
core   +1 more source

The Asymmetric Self‐Replicative Alkylation of N‐Arylaldimines Using Organolithium Reagents

open access: yesChemistry – A European Journal, EarlyView.
Here, we report a new asymmetric autoinductive reaction; the addition of nBuLi to N‐arylaldimines to form chiral lithium amides. The reaction proceeds with full conversion and complete transfer of chirality, representing the first example of an asymmetric autoinductive reaction with organolithium reagents.
Anka Hagelschuer   +2 more
wiley   +1 more source

Maio-junho de 1968 na França: o epicentro de uma crise de hegemonia (parte II)

open access: yesMediações: Revista de Ciências Sociais, 2008
Neste artigo, o autor reexamina a história de um ciclo de lutas sociais, políticas e culturais como epicentro da crise de hegemonia. Na base das principais radicalizações políticas estudantis, operárias e dos novos movimentos sociais do maio-junho de ...
Alain Bihr
doaj  

The effect of synthetic and bovine conjugated linoleic acid on energy balance : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutritional Science at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 1999
Conjugated linoleic acid (CLA) is biologically active and has altered body composition in experimental animals. Dietary supplementation with synthetic CLA reduced body fat in mice and rats in a number of studies.
Hayman, Ann
core  

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