Results 61 to 70 of about 4,717,677 (246)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Al Ibtida: Jurnal Pendidikan Guru MILow learning outcomes and student engagement result from ineffective learning models and media in actively involving students. This study analyzes the effectiveness of the problem-based learning (PBL) model combined with Powtoon media in enhancing ...
Faradina Hibatul Haqqi +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Modeling Students’ Behavioral Engagement Through Different In-class Behavior Styles
, 2023 Supplementary material for the paper: "Modeling Students’ Behavioral Engagement Through Different In-class Behavior Styles"
Luis Felipe Coimbra Costa, Samuel Gomes
core +3 more sources
The Amplify Engagement Report presents findings from the Children with Incarcerated Parents (CHIRP) study, which aims to estimate the number of children affected by parental incarceration across five Canadian provinces (British Columbia, Alberta ...
Engagement, Amplify
core +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2001 University of Minnesota: Office for Public Engagement. (2001). Civic Engagement Inventory.
University of Minnesota: Office for Public Engagement
core
Developing badge eco-systems to support engagement in class-based and online learning [PDF]
, 2016 Background Badges enable academic and non-academic learners to collect and display their achievements and to enhance their training and qualification repertoire.
Hadi, Munib, Petronzi, D., Bryson, David
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source