Results 101 to 110 of about 1,881,470 (286)

The Association of Lipoprotein(a) and Circulating Monocyte Subsets with Severe Coronary Atherosclerosis

Journal of Cardiovascular Development and Disease, 2021
Background and aims: Chronic inflammation associated with the uncontrolled activation of innate and acquired immunity plays a fundamental role in all stages of atherogenesis.
Olga I. Afanasieva, Anastasya Yu. Filatova, Tatiana I. Arefieva, Elena A. Klesareva, Alexandra V. Tyurina, Natalia V. Radyukhina, Marat V. Ezhov, Sergei N. Pokrovsky   +7 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Gene names of 22 salmon module genes and 70 Magenta module genes in non-classical monocytes. [PDF]

, 2023
Gene names of 22 salmon module genes and 70 Magenta module genes in non-classical monocytes.
Karin Mueller (579839), Joan W. Berman (10860768), Klaus Ley (8593), Mardge H. Cohen (7923182), Igho Ofotokun (4059922), Stephen Gange (15674986), Tao Wang (12008), Kathryn Anastos (119435), Alan L. Landay (7919387), Phyllis C. Tien (7923128), Jason M. Lazar (10002157), Howard N. Hodis (9338345), David B. Hanna (10649576), Yanal Ghosheh (3404441), Sonya L. Heath (11605483), Qibin Qi (172143), Erik Ehinger (13558375), Juan Lin (171491), Russell P. Tracy (7300421), Wendy J. Mack (7923125), Chenglong Liu (317596), Robert C. Kaplan (7699334)   +21 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Stem Cell Transplantation in Friedreich Ataxia: Cure for Leukemia but No Effect on Neurological Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Friedreich Ataxia (FRDA) is a neurodegenerative disorder of children and young adults associated with cardiomyopathy and other systemic complications. We report a 10‐year‐old girl who presented simultaneously with Acute Myelogenous Leukemia and FRDA who was successfully treated for her leukemia with allogeneic hematopoietic stem cell ...
Alexandra Gitman, Niyati Bhandari, Maria Castellaro, Kim Schadt, María Cancio, David R. Lynch   +5 more
wiley   +1 more source

Circulating monocyte subsets in multiple myeloma patients receiving autologous stem cell transplantation – a study of the preconditioning status and the course until posttransplant reconstitution for a consecutive group of patients

BMC Immunology, 2019
Background Induction therapy of multiple myeloma patients prior to autologous stem cell transplantation has changed from conventional chemotherapy to treatment based on proteasome inhibitors or immunomodulatory drugs.
Ida Marie Rundgren, Elisabeth Ersvær, Aymen Bushra Ahmed, Anita Ryningen, Øystein Bruserud   +4 more
doaj   +1 more source

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML. [PDF]

Blood, 2017
To the editor: Even though the diagnosis criteria of chronic myelomonocytic leukemia (CMML) have been recently revised by the World Health Organization (WHO),[1][1] recognition of this disease can be challenging.
Dorothée Sélimoglu-Buet, Bouchra Badaoui, E. Benayoun, A. Toma, P. Fenaux, B. Quesnel, G. Étienne, T. Braun, N. Abermil, M. Morabito, N. Droin, E. Solary, O. Wagner-Ballon   +12 more
semanticscholar   +3 more sources

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14+CD16-Monocytes [PDF]

, 2019
Monocytes in humans consist of 3 subsets; CD14+CD16−(classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation.
Bertuzzo Veiga, C (15701750), Shihata, WA (15701747), Palmer, CS (15694022), Cooney, OD (15701753), Claeson, E (15701762), Fleetwood, AJ (15701756), Murphy, AJ (15559433), Lee, MKS (15701741), Flynn, MC (15701759), Henstridge, DC (15701765), Hamilton, JA (15701768), Al-sharea, A (15701744)   +11 more
core  

Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

Frontiers in Immunology
An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established allowing us to explore the development of immunity. In this model, ~55% of volunteers who received the challenge reached typhoid diagnosis criteria (TD), while ~45%
Franklin R. Toapanta, Jingping Hu, Kari Ann Shirey, Paula J. Bernal, Myron M. Levine, Myron M. Levine, Thomas C. Darton, Claire S. Waddington, Andrew J. Pollard, Marcelo B. Sztein, Marcelo B. Sztein, Marcelo B. Sztein   +11 more
doaj   +1 more source