Results 101 to 110 of about 1,360,367 (244)

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14+CD16-Monocytes

, 2019
Monocytes in humans consist of 3 subsets; CD14+CD16−(classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation.
Bertuzzo Veiga, C (15701750), Shihata, WA (15701747), Palmer, CS (15694022), Cooney, OD (15701753), Claeson, E (15701762), Fleetwood, AJ (15701756), Murphy, AJ (15559433), Lee, MKS (15701741), Flynn, MC (15701759), Henstridge, DC (15701765), Hamilton, JA (15701768), Al-sharea, A (15701744)   +11 more
core  

Phenotypic characterization of human intermediate monocytes

Frontiers in Immunology, 2013
Daniëlle eHijdra, Daniëlle eHijdra, Adriane DM Vorselaars, Jan C Grutters, Jan C Grutters, Anke ME Claessen, Ger T Rijkers, Ger T Rijkers, Ger T Rijkers   +8 more
doaj   +1 more source

In vitro Phenotype Induction of Circulating Monocytes: CD16 and CD163 Analysis

Journal of Inflammation Research, 2021
Claudio Karsulovic,1,2 Fabian Tempio,3,4 Mercedes Lopez,3,4 Julia Guerrero,1 Annelise Goecke1,2 1Laboratorio de Inmunomodulación Neuroendocrina, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile ...
Karsulovic C, Tempio F, Lopez M, Guerrero J, Goecke A   +4 more
doaj  

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Peripheral Classic and Intermediate Monocyte Subsets as Immune Biomarkers of Systemic Lupus Erythematosus Disease Activity

Acta Medica Indonesiana
Background: Monocytes are evolutionarily preserved innate immune cells that play essential roles in immune response regulation. Three activated monocyte subsets—classical (CD14++CD16–), intermediate (CD14++CD16+), and nonclassical (CD14+CD16++)—are ...
Amaylia Oehadian, Mohammad Ghozali, Sutiadi Kusuma, Lusi Mersiana, Nadia Gita Ghassani, Fransisca Fransisca, Yitzchak Millenard Sigilipu, Andini Kartikasari, Laniyati Hamijoyo   +8 more
doaj   +2 more sources

Chemotherapy-induced developmental trajectories of monocytes in breast cancer

RUDN Journal of Medicine
Relevance . Monocytes are circulating immune cells which are traditionally divided into three subsets. The contribution of each subset to breast cancer pathogenesis is controversial.
Tatiana S. Gerashchenko, Marina R. Patysheva, Anastasia A. Fedorenko, Anastasia P. Filatova, Maria A. Vostrikova, Olga D. Bragina, Anton A. Fedorov, Pavel S. Iamshchikov, Evgeny V. Denisov   +8 more
doaj   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Phenotypic features and subset composition of monocytes in acute pancreatitis

Медицинская иммунология
The aim of our research was to study the features of activation receptor expression on various subsets of blood monocytes in patients with acute pancreatitis (AP). 69 patients aged 37-62 years with moderateand severe-grade AP were examined. The diagnosis
A. A. Savchenko, D. E. Zdzitovetskiy, M. M. Adilov, I. V. Kudryavtsev, V. D. Belenyuk, A. G. Borisov   +5 more
doaj   +1 more source