Results 91 to 100 of about 14,180 (293)
The claudin family of proteins in human malignancy: a clinical perspective
Cancer Management and Research, 2013 Lei Ding,1,2 Zhe Lu,2,4 Qun Lu,2,3 Yan-Hua Chen2,3 1Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Beijing, People's Republic of China; 2Department of Anatomy and Cell Biology, 3Leo W.
Ding L, Lu Z, Lu Q, Chen YH
doaj
Claudins in human cancer: a review.
Histology and histopathology, 2009 Claudins are tight junction proteins that are critical for the sealing of cellular sheets and controlling paracellular ion flux. The claudin family of proteins is composed of at least 24 closely related transmembrane proteins, most of them are well characterized at the gene and protein levels.
Ouban, Abderrahman, Ahmed, A.
openaire +3 more sources
, 2021 The bacterium Clostridium perfringens causes severe, sometimes lethal gastrointestinal disorders in humans, including enteritis and enterotoxemia. Type F strains produce an enterotoxin (CpE) that causes the third most common foodborne illness in the ...
Vecchio, Alex J. +5 more
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Animal Research and One Health, EarlyView.Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis
Frontiers in Physiology, 2017 Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming TJ proteins allowing calcium and magnesium reabsorption in the thick ascending limb of Henle's
Claire Bardet +11 more
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Claudins and hepatocellular carcinoma
Biomedicine & PharmacotherapyHepatocellular carcinoma (HCC) has a high incidence and dismal prognosis, making it a significant global health burden. To change this, the development of new therapeutic strategies is imminent. The claudin (CLDN) family, as key components of tight junctions (TJs), plays an important role in the initiation and development of cancer.
Wentao Wang +4 more
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Animal Research and One Health, EarlyView.Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar +8 more
wiley +1 more source
Effects of ZO-1 knockout on the localization and expression levels of claudins.
, 2014 (A) Effects of ZO-1 knockout on the localization of claudins. Control and ZO-1 knockout cells of clone 1 were co-cultured on filter inserts. Signal intensity of claudins on lines shown in confocal microscopic images (arrows) were analyzed.
Mikio Furuse (621728) +2 more
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Modulation of Animal Gut Health by Milk Oligosaccharide
Animal Research and One Health, EarlyView.This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen +7 more
wiley +1 more source