Results 161 to 170 of about 20,395 (312)
Histopathology, EarlyView.CLDN18 (43‐14A) is expressed in most gastric type adenocarcinomas and a much smaller proportion of HPV‐associated adenocarcinomas. Expression of CLDN18.2 mRNA but not CLDN18.1 mRNA is confirmed in both gastric type adenocarcinomas and HPV‐associated adenocarcinomas.
Nobuko Yasutake +12 more
wiley +1 more source
Molecular pathology of phyllodes tumours of the breast—much more than MED12
Histopathology, EarlyView.Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang +3 more
wiley +1 more source
Claudins proteins in brain tumors: expression patterns and therapeutic target. [PDF]
Biochem Med (Zagreb)Romanowicz A +2 more
europepmc +1 more source
Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases
Journal of Gastroenterology and Hepatology, EarlyView.Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li +3 more
wiley +1 more source
Tight junction proteins: Gatekeepers turned facilitators in the pathogenesis of gastric adenocarcinoma. [PDF]
World J Gastrointest OncolSelvam S, Vairappan B.
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats
Neurogastroenterology &Motility, EarlyView.Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao +6 more
wiley +1 more source
Control of renal calcium permeability via a tight junctional claudin switch. [PDF]
Proc Natl Acad Sci U S Avan der Veen RE +5 more
europepmc +1 more source
Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption
Obesity Reviews, EarlyView.ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg +3 more
wiley +1 more source