Polymorphic light eruption shows aberrant expression of epidermal tight junction proteins in unexposed and UVR-exposed skin: an experimental study. [PDF]
Pond E +4 more
europepmc +1 more source
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
Architecture, permeability, disruption dynamics and remodeling of tight junction proteins: Implications for performance, health, and welfare of the broiler chicken. [PDF]
Hossain ME, Munni MB, Islam S.
europepmc +1 more source
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang +9 more
wiley +1 more source
Food-derived molecules as regulators of intestinal tight junctions and barrier function: mechanisms and implications. [PDF]
Ryan SM, Brayden DJ.
europepmc +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
The IQGAP1-claudin cell junction axis in cisplatin-induced epithelial damage. [PDF]
Barudi Y +6 more
europepmc +1 more source
The role of neutrophils in the pathophysiology of inflammatory bowel diseases
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens +8 more
wiley +1 more source
Claudin-Claudin Interactions, Practical Examples
openaire +1 more source
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng +4 more
wiley +1 more source

