Results 211 to 220 of about 20,650 (306)

Metabolic Reprogramming and GM‐CSF Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression

Oral Diseases, EarlyView.
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang, Chang‐Wei Su, Chih‐Huang Tseng, Pang‐Yu Chen, Hieu D. H. Nguyen, Leong‐Perng Chan, Yuk‐Kwan Chen, Shih Sheng Jiang, Steven Lo, Shyng‐Shiou F. Yuan   +9 more
wiley   +1 more source

Involvement of claudins 6 and 9 in epithelial-mesenchymal transition and the metastatic process. [PDF]

Tissue Barriers
Diego NE, Montaño LF, Rendón-Huerta EP.   +2 more
europepmc   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

Periodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens, Ekin Yay‐Kus, Rafael Scaf de Molon, Viorelia Stoica, Peter Rimmer, Josefine Hirschfeld, Asif Jilani Iqbal, Tariq Iqbal, Iain Chapple   +8 more
wiley   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Reduced Claudin-3 Expression Is Linked to Unfavorable Tumor Features and Poor Prognosis in Non-Small Cell Lung Cancer. [PDF]

Lung Cancer (Auckl)
Schraps N, Reck M, Hantzsch-Kuhn B, Olchers T, Ellebrecht DB, Möller K, Fraune C, Lennartz M, Lutz F, Kluth M, Makrypidi-Fraune G, Simon R, Sauter G, Steurer S, Von Weihe S.   +14 more
europepmc   +1 more source

Prebiotic Bimuno® GOS reduces illness symptoms and supports gut barrier function and immunity after intermittent exercise in the heat

Experimental Physiology, EarlyView.
Abstract Exercise in hot climates increases the risk of gastrointestinal (GI) disruption and respiratory illness. We investigated the effects of a 42 day prebiotic intervention on markers of intestinal epithelial injury, GI discomfort and immunity following football specific exercise in the heat and daily upper respiratory illness.
Connor J. Parker, Samantha J. Abbott, Luke R. Butterfield, Kirsty A. Hunter, Michael A. Johnson, Graham R. Sharpe, Neil C. Williams   +6 more
wiley   +1 more source

Impact of PAR2 on Tight Junctions and Esophageal Mucosal Inflammation in Rats with Gastroesophageal Reflux Disease. [PDF]

Neurogastroenterol Motil
Du M, Wang L, Duan W, Wang W, Fu W, Sun Y.   +5 more
europepmc   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Claudin18.2 as a Promising Therapeutic Target in Gastric Cancer. [PDF]

Cells
Poniewierska-Baran A, Plewa P, Żabicka Z, Pawlik A.   +3 more
europepmc   +1 more source

Claudin-Claudin Interactions, Practical Examples

Biomedical Journal of Scientific & Technical Research
openaire   +1 more source