Results 31 to 40 of about 1,290,910 (349)
Organotitanium Click Chemistry
Fine Chemical Engineering, 2023 The click chemistry of titanium exemplified by the “green” [3+2] cycloaddition of the [Ti-N3] moiety with nitriles RCN to form a tetrazole ligand, is currently limited in scope, but the future of this open and wide field is bright, full of promising new synthetic approaches discussed herein, for pharmacological and bio orthogonal applications.
openaire +1 more source
Oxidation-Induced “One-Pot” Click Chemistry
Chemical Reviews, 2021 Click chemistry has been established rapidly as one of the most valuable methods for the chemical transformation of complex molecules. Due to the rapid rates, clean conversions to the products, and compatibility of the reagents and reaction conditions ...
Bauke Albada +3 more
semanticscholar +1 more source
Stable covalently photo-cross-linked poly(ionic liquid) membrane with gradient pore size
, 2017 An imidazolium-based poly(ionic liquid) is covalently cross-linked via UV light-induced thiolene (click) chemistry to yield a stable porous polyelectrolyte membrane with gradients of crosslink density and pore size distribution along its cross-section ...
Dani, Alessandro +4 more
core +1 more source
Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]
, 2015 The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy +3 more
core +2 more sources
, 2019 Click chemistry has found wide application in bioconjugation, enabling control over the site of modification in biomolecules. Demonstrations of this chemistry to construct chemically defined antibody-drug conjugates (ADCs) have increased in recent years, following studies that support benefits of homogeneity and site-specificity of drug placement on ...
Tak Ian Chio, Susan Bane
openaire +4 more sources
Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]
, 2017 Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin +7 more
core +1 more source
Application of “Click” Chemistry in Biomedical Hydrogels
ACS Omega, 2022 Since “click” chemistry was first reported in 2001, it has remained a popular research topic in the field of chemistry due to its high yield without byproducts, fast reaction rate, simple reaction, and biocompatibility.
X. Li, Yuzhu Xiong
semanticscholar +1 more source
Metal free click chemistry on nucleosides and oligonucleotides [PDF]
, 2015 Chemoselective ligation of biologically significant moieties through azide alkyne Click Chemistry has recently received much attention1. The reaction is attractive in that it regioselectively affords stable triazole linked bioconjugated products under ...
Batchelor, Caroline +3 more
core +1 more source
Metal-Free Click-Chemistry: A Powerful Tool for Fabricating Hydrogels for Biomedical Applications
Bioconjugate chemistryIncreasing interest in the utilization of hydrogels in various areas of biomedical sciences ranging from biosensing and drug delivery to tissue engineering has necessitated the synthesis of these materials using efficient and benign chemical ...
Aysun Degirmenci, R. Sanyal, A. Sanyal
semanticscholar +1 more source