Results 31 to 40 of about 327,716 (251)

Click Chemistry in Human Cancer Research

open access: yesZhongliu Fangzhi Yanjiu
As one of the typical bioorthogonal chemistry reactions, click chemistry joins molecules similar to “Lego”. Bioorthogonal click chemistry is used to modify cancer cells, design antitumor drugs, delivery drugs, manipulate immune cells, and help ...
Baihong ZHANG, Hongyun YUE
doaj   +2 more sources

Click Chemistry in Materials Science [PDF]

open access: yes, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106803/1/adfm201302847 ...
Bowman, Christopher N.   +3 more
core   +1 more source

Siloxane crosslinks with dynamic bond exchange enable shape programming in liquid-crystalline elastomers [PDF]

open access: yesScientific Reports (2020) 10:6609, 2019
Liquid crystalline elastomers (LCE) undergo reversible shape changes in response to stimuli, which may enable a wide range of smart applications, such as soft robot, adhesive systems or implantable medical devices. Here we introduce new dynamic covalent chemistry based on siloxane equilibrium exchange into the LCE to enable processing (director ...
arxiv   +1 more source

Green Approach in Click Chemistry [PDF]

open access: yes, 2018
The aim of the topic on click chemistry is used to synthesize various derivatives of 1, 2, 3-triazol-1-yl piperazine, 1, 2, 3-triazol-1-yl quinoxaline, one pot 1,2,3-triazole and bistriazole.
Sachin P. Shirame, Raghunath B. Bhosale
openaire   +5 more sources

Click chemistry in the design of AIEgens for biosensing and bioimaging

open access: yesAggregate, 2023
The development of rapid, selective, and sensitive fluorescent sensors is essential for visualizing and quantifying biological molecules and processes in vitro, ex vitro, and in vivo, which is important for not only fundamental biological studies but the
Marie‐Claire Giel, Yuning Hong
doaj   +1 more source

Cavity Click Chemistry: Cavity-Catalyzed Azide-Alkyne Cycloaddition [PDF]

open access: yesarXiv, 2023
Click chemistry, which refers to chemical reactions that are fast, selective, and with high product yields, has become a powerful approach in organic synthesis and chemical biology. Due to the cytotoxicity of the transition metals employed in click chemistry reactions, a search for novel metal-free alternatives continues.
arxiv  

Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]

open access: yes, 2013
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa   +8 more
core   +1 more source

Click Metamaterials: Fast Acquisition of Thermal Conductivity and Functionality Diversities [PDF]

open access: yesarXiv, 2023
Material science is an important foundation of modern society development, covering significant areas like chemosynthesis and metamaterials. Click chemistry provides a simple and efficient paradigm for achieving molecular diversity by incorporating modified building blocks into compounds.
arxiv  

The Reaction Mechanism of the Azide-Alkyne Huisgen Cycloaddition [PDF]

open access: yesPhys. Chem. Chem. Phys., 2019, 21, 19281-19287, 2020
The azide-alkyne Huisgen cycloaddition has a key role in click chemistry and configures as powerful tool in pharmaceutical and medicinal chemistry. Although this reaction has already been largely studied, there is an ongoing debate about its mechanism. In this work we study the dynamical aspects of the process using metadynamics computer simulation. We
arxiv   +1 more source

Nanoplasmonics tuned “click chemistry” [PDF]

open access: yesNanoscale, 2016
Nanoplasmonics is a growing field of optical condensed matter science dedicated to optical phenomena at the nanoscale level in metal systems. Extensive research on noble metallic nanoparticles (NPs) has emerged within the last two decades due to their ability to keep the optical energy concentrated in the vicinity of NPs, in particular, the ability to ...
Tijunelyte, I.   +6 more
openaire   +4 more sources

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