Results 21 to 30 of about 5,177,092 (374)

Synthesis of Terpolymers by Click Reactions [PDF]

open access: yesChemistry – An Asian Journal, 2011
AbstractWell‐defined polymeric structures were easily generated through living polymerization systems, in particular, living radical polymerizations. The polymeric precursors with orthogonal functionalities were subsequently clicked together with single or double (combinatorial) click reactions, such as the copper‐catalyzed azide–alkyne cycloadditions (
Ozcan, Altintas, Umit, Tunca
openaire   +2 more sources

A method for parallel microscale protein labeling and precise control over the average degree of labeling (aDoL)

open access: yesScientific Reports, 2023
A widely used approach for protein conjugation is through the lysine residues reacting with NHS- or other active esters. However, it is a challenge to precisely control the degree of labeling (DoL) due to the instability of active ester and variability ...
Qiaoqiao Ruan, Cheng Zhao
doaj   +1 more source

A New Methodology for Assessing Macromolecular Click Reactions and Its Application to Amine--Tertiary Isocyanate Coupling for Polymer Ligation. [PDF]

open access: yes, 2016
Click reactions have provided access to an array of remarkably complex polymer architectures. However, the term "click" is often applied inaccurately to polymer ligation reactions that fail to respect the criteria that typify a true "click" reaction ...
Gody, Guillaume   +3 more
core   +4 more sources

Selective C(sp2)−H Halogenation of "click" 4-Aryl-1,2,3-triazoles [PDF]

open access: yes, 2017
Selective bromination reactions of “click compounds” are described. Electron-neutral and electron-deficient arenes selectively undergo unprecedented Pd-catalyzed C–H ortho-halogenations assisted by simple triazoles as modular directing groups, whereas ...
Correa Navarro, Arkaitz   +2 more
core   +2 more sources

Polymer Nanocomposites via Click Chemistry Reactions [PDF]

open access: yesPolymers, 2017
The emerging areas of polymer nanocomposites, as some are already in use in industrial applications and daily commodities, have the potential of offering new technologies with all manner of prominent capabilities. The incorporation of nanomaterials into polymeric matrix provides significant improvements, such as higher mechanical, thermal or electrical
Mehmet Arslan, Mehmet Tasdelen
openaire   +2 more sources

GEN-Click: Genetically Encodable Click Reactions for Spatially Restricted Metabolite Labeling

open access: yesACS Central Science, 2023
Chemical reactions for the in situ modification of biomolecules within living cells are under development. Among these reactions, bio-orthogonal reactions such as click chemistry using copper(I) and Staudinger ligation are widely used for specific biomolecule tracking in live systems.
Pratyush Kumar Mishra   +4 more
openaire   +4 more sources

Intramolecular bridges formed by photoswitchable click amino acids

open access: yesBeilstein Journal of Organic Chemistry, 2012
Photoswitchable click amino acids (PSCaa) are amino acids bearing a side chain consisting of a photoswitchable unit elongated with a functional group that allows for a specific click reaction, such as an alkene that can react with the thiol group of a ...
Christian Hoppmann   +2 more
doaj   +1 more source

Application of click chemistry in nanoparticle modification and its targeted delivery

open access: yesBiomaterials Research, 2018
Background Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparticle research is a representative ...
Gawon Yi   +4 more
doaj   +1 more source

Exploration of Optical Properties of Novel Pyrene Derivatives Modified by Click Functionalization

open access: yesCrystals, 2022
A simple synthetic method was designed, in which the Sonogashira coupling reaction and [2+2] cycloaddition click reaction with high yield were performed on 1-bromopyrene to obtain several novel pyrene derivatives.
Yang Yu   +7 more
doaj   +1 more source

In situ click chemistry generation of cyclooxygenase-2 inhibitors

open access: yesNature Communications, 2017
Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with several cancers and neurodegenerative diseases.
A. Bhardwaj, J. Kaur, M. Wuest, F. Wuest
semanticscholar   +1 more source

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