Results 21 to 30 of about 595,480 (188)

Application of click chemistry in nanoparticle modification and its targeted delivery

Biomaterials Research, 2018
Background Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparticle research is a representative ...
Gawon Yi, Jihwan Son, Jihye Yoo, Changhee Park, Heebeom Koo   +4 more
doaj   +1 more source

Comparison of Characteristics and DNAzyme Activity of G4–Hemin Conjugates Obtained via Two Hemin Attachment Methods

Molecules, 2018
Two conjugation methods using different linkers were applied for the investigation of the spectral characteristics and activity of G-quadruplex (G4)–hemin conjugates.
Joanna Kosman, Krzysztof Żukowski, Bernard Juskowiak   +2 more
doaj   +1 more source

Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry [PDF]

, 2011
Aim of this study was the site-specific conjugation of an epidermal growth factor (EGF)-polyethylene glycol (PEG) chain by click chemistry onto a poly(amido amine) (PAMAM) dendron, as a key step toward defined multifunctional carriers for targeted gene ...
Balogh L., Bartlett D. W., Blessing T., Boeckle S., Boussif O., Carboni B., Carlin C. R., Choi J. S., Christian Dohmen, Davis M. E., Davis M. E., de Bruin K., Ernst Wagner, Esfand R., Haijun Yu, Hua C., Iyer J., Kannan R. M., Kataoka K., Kircheis R., Kircheis R., Kloeckner J., Kloeckner J., Kursa M., Lee J. W., Li S. D., Luo D., Lutz J. F., Maeda H., Maiti P. K., Meyer M., Navarro G., Nie Y., Ogris M., Plank C., Plank C., Russ V., Russ V., Russ V., Schaffert D., Shir A., Simoes S., Svenson S., Tomalia D. A., Tomalia D. A., von Gersdorff K., Wagner E., Wagner E., Walker G. F., Wolschek M. F., Wood K. C., Yellepeddi V. K., Yu H., Yu H., Yu Nie, Yunqiu Li, Zhang X. Q., Zhao X., Zou S. M., Zugates G. T.   +59 more
core   +1 more source

A dark intermediate in the fluorogenic reaction between tetrazine fluorophores and trans-cyclooctene

Biophysical Reports, 2022
Fluorogenic labeling via bioorthogonal tetrazine chemistry has proven to be highly successful in fluorescence microscopy of living cells. To date, trans-cyclooctene (TCO) and bicyclonyne have been found to be the most useful substrates for live-cell ...
Felix Hild, Philipp Werther, Klaus Yserentant, Richard Wombacher, Dirk-Peter Herten   +4 more
doaj   +1 more source

Efficient click-addition sequence for polymer–polymer couplings [PDF]

, 2016
Controlled radical polymerization methods and click chemistry form a versatile toolbox for creating complex polymer architectures. However, the incompatibility between the functional groups required for click reactions and the reaction conditions of ...
Brendel, Johannes C., Gody, Guillaume, Perrier, Sébastien   +2 more
core   +1 more source

Conformation of G-quadruplex Controlled by Click Reaction

Molecules, 2020
G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging.
Chao-Da Xiao, Zhi-Yong He, Chuan-Xin Guo, Xiang-Chun Shen, Yan Xu   +4 more
doaj   +1 more source

Triarylborane-“Click” Fluorescent Tag for Orthogonal Amino Acid Labelling, Interactions with DNA, Protein, and Cyclodextrins

Pharmaceuticals, 2023
The innovative design of a triarylborane (TB)-dye with one NMe2-alkylated (propargylated) group and one NMe2 group yielded a system that is both an NMe2 π-donor and an inductive NMe2-alkyl cationic acceptor.
Marta Jurković, Matthias Ferger, Isabela Drašković, Todd B. Marder, Ivo Piantanida   +4 more
doaj   +1 more source

Triazolinediones as highly enabling synthetic tools [PDF]

, 2016
Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat "exotic" reputation.
Billiet, Stijn, Chattopadhyay, Subrata, De Bruycker, Kevin, Du Prez, Filip, Houck, Hannes, Winne, Johan   +5 more
core   +1 more source

Click histochemistry for whole-mount staining of brain structures

MethodsX, 2019
Labeling of the replicating DNA with synthetic thymidine analogs is commonly used for marking the dividing cells. However, until now this method has only been applied to histological sections.
Alexander A. Lazutkin, Sergey A. Shuvaev, Natalia V. Barykina   +2 more
doaj   +1 more source

Acetoacetate based thermosets prepared by dual-Michael addition reactions [PDF]

, 2019
A novel set of dual-curable multiacetoacetate-multiacrylate-divinyl sulfone ternary materials with versatile and manipulable properties are presented.
Fernández Francos, Xavier, Konuray, Ali Osman, Ramis Juan, Xavier, Serra Albet, Maria Àngels   +3 more
core   +2 more sources