Results 91 to 100 of about 1,786,363 (358)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Target Gene Inactivation in Cyanobacterium Anabaena sp. PCC 7120

Bio-Protocol, 2016
Anabaena sp. strain PCC 7120 has long served as a model organism for investigating N2-fixation, photosynthesis, and various plant-type metabolic pathways and biofuel production, as well as cellular differentiation (Xu et al., 2008, Halfmann et al., 2014,
Kangming Chen, Huilan Zhu, Liping Gu, Shengni Tian, Ruanbao Zhou   +4 more
doaj   +1 more source

Cloning of the pig renal organic anion transporter 1 (pOAT1)

Biochimie, 2002
A pig kidney cDNA library was screened for the porcine ortholog of the multispecific organic anion transporter 1 (pOAT1). Several positive clones were isolated resulting in two alternatively spliced cDNA clones of pOAT1 (pOAT1 and pOAT1A). pOAT1-cDNAs consist of 2126 or 1895 base pairs (EMBL Acc. No.
Hagos, Yohannes, Bahn, A., Asif, Abdul Rahman, Krick, W., Sendler, M., Burckhardt, Gerhard   +5 more
openaire   +3 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics. [PDF]

, 2014
BackgroundAnimal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries.
Ayoub, Nadia A, Clarke, Thomas H, Garb, Jessica E, Haney, Robert A, Hayashi, Cheryl Y   +4 more
core   +2 more sources

Molecular characterization of a novel intracellular ADP-ribosyl cyclase.

PLoS ONE, 2007
BackgroundADP-ribosyl cyclases are remarkable enzymes capable of catalyzing multiple reactions including the synthesis of the novel and potent intracellular calcium mobilizing messengers, cyclic ADP-ribose and NAADP.
Dev Churamani, Michael J Boulware, Timothy J Geach, Andrew C R Martin, Gary W Moy, Yi-Hsien Su, Victor D Vacquier, Jonathan S Marchant, Leslie Dale, Sandip Patel   +9 more
doaj   +1 more source

cDNA cloning and characterization of three genes uniquely expressed in cerebellum by Purkinje neurons

Journal of Neuroscience, 1988
The characteristics that distinguish the different neuronal cell types of an organism are believed to be primarily determined by unique patterns of cellular gene expression.
D. Nordquist, C. Kozak, H. Orr
semanticscholar   +1 more source

Quantum Emitters in Hexagonal Boron Nitride: Principles, Engineering and Applications

Advanced Functional Materials, EarlyView.
Quantum emitters in hexagonal boron nitride have emerged as a promising candidate for quantum information science. This review examines the fundamentals of these quantum emitters, including their level structures, defect engineering, and their possible chemical structures.
Thi Ngoc Anh Mai, Md Shakhawath Hossain, Nhat Minh Nguyen, Yongliang Chen, Chaohao Chen, Xiaoxue Xu, Quang Thang Trinh, Toan Dinh, Toan Trong Tran   +8 more
wiley   +1 more source

Strategies for the evolution of sex [PDF]

, 2001
We find that the hypothesis made by Jan, Stauffer and Moseley [Theory in Biosc., 119, 166 (2000)] for the evolution of sex, namely a strategy devised to escape extinction due to too many deleterious mutations, is sufficient but not necessary for the ...
A. Bernardes, A. Kondrashov, A. Pekalski, Ayşe Erzan, B. Chopard, B. Drossel, B. Örcal, C. Chisholm, D. Stauffer, D. Stauffer, E.J. Lyons, E.P. Solomon, Erkan Tüzel, H.L. Muller, J. Maynard Smith, J. Maynard Smith, J. Maynard Smith, J. Thoms, J.M. Smith, J.S. SaMartins, L.M. Prescott, M. Eigen, N. Jan, R.J. Redfield, S.S. Mader, T.J. Penna, Volkan Sevim, W.D. Hamilton, Y. Cui   +28 more
core   +2 more sources

Parallel DNA pyrosequencing unveils new zebrafish microRNAs

BMC Genomics, 2009
Background MicroRNAs (miRNAs) are a new class of small RNAs of approximately 22 nucleotides in length that control eukaryotic gene expression by fine tuning mRNA translation.
Arrais Joel, Gomes Ana C, Egas Conceição, Santos Bruno, Pereira Patrícia M, Soares Ana R, Oliveira José L, Moura Gabriela R, Santos Manuel AS   +8 more
doaj   +1 more source