Results 171 to 180 of about 169,769 (295)
In- & Out-Cloning: plasmid toolboxes for scarless transcription unit and modular Golden Gate acceptor plasmid assembly. [PDF]
de Vries ST+3 more
europepmc +1 more source
This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado+10 more
wiley +1 more source
How many plasmids can bacteria carry? A synthetic biology perspective. [PDF]
Kiattisewee C.
europepmc +1 more source
Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen+7 more
wiley +1 more source
Genetic- and culture-based tools for studying <i>Bacteroides fragilis</i>. [PDF]
Schnizlein MK+3 more
europepmc +1 more source
DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai+8 more
wiley +1 more source
Synthetic Cells, Synthetic Life, and Inheritance [PDF]
Knapland, Kristine S.
core +1 more source
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu+15 more
wiley +1 more source
Transferable approaches to CRISPR-Cas9 induced genome editing in non-model insects: a brief guide. [PDF]
Ahmed HMM, Zheng L, Hunnekuhl VS.
europepmc +1 more source