Molecular Studies on Preproinsulin Gene
MATEC Web of Conferences, 2016 Insulin plays an important role in maintaining the blood glucose level of the body. The β-cells of pancreas produce insulin in the form of precursor that is preproinsulin.
Sabir Sarah, Younas Hooria
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Estimating genetic variability in non-model taxa: a general procedure for discriminating sequence errors from actual variation. [PDF]
PLoS ONE, 2010 Genetic variation is the driving force of evolution and as such is of central interest for biologists. However, inadequate discrimination of errors from true genetic variation could lead to incorrect estimates of gene copy number, population genetic ...
Karen Dawson +2 more
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MOLECULAR CLONING OF α-AMYLASE GENES FROM DROSOPHILA MELANOGASTER. II. CLONE ORGANIZATION AND VERIFICATION [PDF]
Genetics, 1985 ABSTRACT Restriction maps of an α-amylase structural gene clone, λDm65, and of four putative α-amylase pseudogene clones are presented. Two α-amylase structural genes, inverted with respect to each other, are contained in λDm65. Subregions of internal DNA sequence homology within λDm65 and of cross-homology between the presumptive ...
J N, Levy, R M, Gemmill, W W, Doane
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Shotgun Phage Display - Selection for Bacterial Receptins or other Exported Proteins
Biological Procedures Online, 2003 Shotgun phage display cloning involves construction of libraries from randomly fragmented bacterial chromosomal DNA, cloned genes, or eukaryotic cDNAs, into a phagemid vector.
Jacobsson Karin +3 more
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Nucleic Acids Research, 2009 Direct cloning and parallel sequencing, an extremely powerful method for microRNA (miRNA) discovery, has not yet been applied to bacterial transcriptomes. Here we present sRNA-Seq, an unbiased method that allows for interrogation of the entire small, non-
Jane M. Liu +5 more
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Developments in the tools and methodologies of synthetic biology. [PDF]
, 2014 Synthetic biology is principally concerned with the rational design and engineering of biologically based parts, devices, or systems. However, biological systems are generally complex and unpredictable, and are therefore, intrinsically difficult to ...
Freemont, P +3 more
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Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]
, 2014 Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K +8 more
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Seven-fluorochrome mouse M-FISH for high-resolution analysis of interchromosomal rearrangements [PDF]
, 2003 The mouse has evolved to be the primary mammalian genetic model organism. Important applications include the modeling of human cancer and cloning experiments. In both settings, a detailed analysis of the mouse genome is essential.
Geigl, J. +3 more
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Emerging technologies to create inducible and genetically defined porcine cancer models
Frontiers in Genetics, 2016 There is an emerging need for new animal models that address unmet translational cancer research requirements. Transgenic porcine models provide an exceptional opportunity due to their genetic, anatomic and physiological similarities with humans.
Lawrence B Schook +6 more
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Genes & Development, 1994 During Dictyostelium development, the cAMP-regulated induction of cell-type-specific late genes marks a developmental switch from the initial formation of the multicellular organism to the differentiation of the various cell types that mediate ...
Gavin R. Schnitzler +2 more
semanticscholar +1 more source