Results 61 to 70 of about 1,642,375 (296)

Cloning and Functional Expression of A Mouse Liver Organic Cation Transporter [PDF]

Hepatology, 1999
Hepatic uptake of organic cations is essential for the metabolism and secretion of numerous endobiotics and drugs. Several hepatic organic cation transporters have been kinetically defined, yet have not been isolated or cloned.
Richard M. Green, Richard M. Green, Coreen Sterritt, David R. Beier, Kathy Lo   +4 more
openaire   +3 more sources

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Implicaciones éticas de la transgénesis y la clonación Ethic implications of transgenesis and cloning

Humanidades Médicas, 2003
La biotecnología, aunque tan antigua como la invención del vino y la fermentación de la cerveza por el hombre, tiene en los años 60 del siglo XX, un importante despegue con las técnicas de biología molecular y clonaje de genes foráneos en organismos ...
Ayní Rodríguez Pargas, Jesús Arturo Junco Barranco, Aymed de la C Rodríguez Pargas, María Antonia de la Cruz Cardoso   +3 more
doaj  

Mos1 Element-Mediated CRISPR Integration of Transgenes in Caenorhabditis elegans

G3: Genes, Genomes, Genetics, 2019
The introduction of exogenous genes in single-copy at precise genomic locations is a powerful tool that has been widely used in the model organism Caenorhabditis elegans.
Nicholas S. Philip, Fernando Escobedo, Laura L. Bahr, Brandon J. Berry, Andrew P. Wojtovich   +4 more
doaj   +1 more source

Cloning of the pig renal organic anion transporter 1 (pOAT1)

Biochimie, 2002
A pig kidney cDNA library was screened for the porcine ortholog of the multispecific organic anion transporter 1 (pOAT1). Several positive clones were isolated resulting in two alternatively spliced cDNA clones of pOAT1 (pOAT1 and pOAT1A). pOAT1-cDNAs consist of 2126 or 1895 base pairs (EMBL Acc. No.
Hagos, Yohannes, Bahn, A., Asif, Abdul Rahman, Krick, W., Sendler, M., Burckhardt, Gerhard   +5 more
openaire   +4 more sources

Structurally Colored Physically Unclonable Functions with Ultra‐Rich and Stable Encoding Capacity

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
This study reports a design strategy for generating bright‐field resolvable physically unclonable functions with extremely rich encoding capacity coupled with outstanding thermal and chemical stability. The optical response emerges from thickness‐dependent structural color formation in ZnO features, which are fabricated by physical vapor deposition ...
Abidin Esidir, Miaoning Ren, Sami Pekdemir, Mustafa Kalay, Nilgun Kayaci, Nail Gunaltay, Hakan Usta, Xian Huang, Mustafa Serdar Onses   +8 more
wiley   +1 more source

Carbonic anhydrase 5 regulates acid-base homeostasis in zebrafish.

PLoS ONE, 2012
The regulation of the acid-base balance in cells is essential for proper cellular homeostasis. Disturbed acid-base balance directly affects cellular physiology, which often results in various pathological conditions. In every living organism, the protein
Ruben Postel, Arnoud Sonnenberg
doaj   +1 more source

A type I peritrophic matrix protein from the malaria vector Anopheles gambiae binds to chitin. Cloning, expression, and characterization.

Journal of Biological Chemistry, 1998
Upon feeding, mosquito midguts secrete the peritrophic matrix (PM), an extracellular chitin-containing envelope that completely surrounds the blood meal. Because the malaria parasite must cross the PM to complete its life cycle in the mosquito, the PM is
Zhicheng Shen, M. Jacobs-Lorena
semanticscholar   +1 more source

Persistence of Dominant T Cell Clones in Accepted Solid Organ Transplants [PDF]

The Journal of Immunology, 2001
Abstract Donor/recipient MHC class II matching is beneficial to the survival of allogeneic kidneys in humans and swine. In the latter, tolerance to class I-disparate grafts can be induced by a short course of immunosuppression, a peripheral mechanism that implicates regulatory T cells.
Christophe Baron, Isabel M. McMorrow, Christian LeGuern, David H. Sachs   +3 more
openaire   +3 more sources