Results 81 to 90 of about 1,771,671 (365)

Molecular Identification of tw5: Vps52 Promotes Pluripotential Cell Differentiation through Cell–Cell Interactions

Cell Reports, 2012
After implantation, pluripotent epiblasts are converted to embryonic ectoderm through cell–cell interactions that significantly change the transcriptional and epigenetic networks.
Michihiko Sugimoto, Masayo Kondo, Michiko Hirose, Misao Suzuki, Kazuyuki Mekada, Takaya Abe, Hiroshi Kiyonari, Atsuo Ogura, Nobuo Takagi, Karen Artzt, Kuniya Abe   +10 more
doaj   +1 more source

Integrating cognitive map learning and active inference for planning in ambiguous environments [PDF]

arXiv, 2023
Living organisms need to acquire both cognitive maps for learning the structure of the world and planning mechanisms able to deal with the challenges of navigating ambiguous environments. Although significant progress has been made in each of these areas independently, the best way to integrate them is an open research question.
arxiv  

Cloning of the pig renal organic anion transporter 1 (pOAT1)

Biochimie, 2002
A pig kidney cDNA library was screened for the porcine ortholog of the multispecific organic anion transporter 1 (pOAT1). Several positive clones were isolated resulting in two alternatively spliced cDNA clones of pOAT1 (pOAT1 and pOAT1A). pOAT1-cDNAs consist of 2126 or 1895 base pairs (EMBL Acc. No.
Hagos, Yohannes, Bahn, A., Asif, Abdul Rahman, Krick, W., Sendler, M., Burckhardt, Gerhard   +5 more
openaire   +4 more sources

Cloning and Functional Expression of A Mouse Liver Organic Cation Transporter [PDF]

Hepatology, 1999
Hepatic uptake of organic cations is essential for the metabolism and secretion of numerous endobiotics and drugs. Several hepatic organic cation transporters have been kinetically defined, yet have not been isolated or cloned.
Richard M. Green, Richard M. Green, Coreen Sterritt, David R. Beier, Kathy Lo   +4 more
openaire   +3 more sources

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Identification of genes involved in xylose metabolism of Meyerozyma guilliermondii and their genetic engineering for increased xylitol production

AMB Express, 2020
Meyerozyma guilliermondii, a non-conventional yeast that naturally assimilates xylose, is considered as a candidate for biotechnological production of the sugar alternative xylitol. Because the genes of the xylose metabolism were yet unknown, all efforts
Denise Atzmüller, Nadine Ullmann, Alexander Zwirzitz   +2 more
doaj   +1 more source

Cell type composition and circuit organization of neocortical radial clones [PDF]

, 2019
SummaryExcitatory neurons arising from a common progenitor establish radially-oriented clonal units in the neocortex which have been proposed to serve as elementary information processing modules. To characterize the cell types and circuit diagram within these clonal units, we performed single-cell RNA-sequencing and multi-cell patch clamp recordings ...
R. James Cotton, Andreas S. Tolias, Andreas S. Tolias, Rickard Sandberg, Fabian H. Sinz, Fabian H. Sinz, Philipp Berens, Cathryn R. Cadwell, Cathryn R. Cadwell, Paul G. Fahey, Federico Scala, Xiaolong Jiang, Shuang Li, Per Johnsson, Dmitry Kobak   +14 more
openaire   +3 more sources

Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]

, 2014
Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K, Gouliouris, T, Harris, KA, Hartley, JC, Jalili, S, Munthali, P, NiRiain, U, Williams, OM, Yam, T   +8 more
core   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

Implicaciones éticas de la transgénesis y la clonación Ethic implications of transgenesis and cloning

Humanidades Médicas, 2003
La biotecnología, aunque tan antigua como la invención del vino y la fermentación de la cerveza por el hombre, tiene en los años 60 del siglo XX, un importante despegue con las técnicas de biología molecular y clonaje de genes foráneos en organismos ...
Ayní Rodríguez Pargas, Jesús Arturo Junco Barranco, Aymed de la C Rodríguez Pargas, María Antonia de la Cruz Cardoso   +3 more
doaj