Engineering of vitamin prototrophy in Clostridium ljungdahlii and Clostridium autoethanogenum [PDF]
Appl Microbiol Biotechnol, 2019 Clostridium autoethanogenum and Clostridium ljungdahlii are physiologically and genetically very similar strict anaerobic acetogens capable of growth on carbon monoxide as sole carbon source.
Humphreys, Christopher M. +8 more
core +5 more sources
Enzyme-constrained metabolic model and in silico metabolic engineering of Clostridium ljungdahlii for the development of sustainable production processes [PDF]
Computational and Structural Biotechnology Journal, 2023 Constraint-based genome-scale models (GEMs) of microorganisms provide a powerful tool for predicting and analyzing microbial phenotypes as well as for understanding how these are affected by genetic and environmental perturbations.
Antonio Caivano +3 more
doaj +3 more sources
Biofilm Formation by Clostridium ljungdahlii Is Induced by Sodium Chloride Stress: Experimental Evaluation and Transcriptome Analysis. [PDF]
PLoS ONE, 2017 The acetogen Clostridium ljungdahlii is capable of syngas fermentation and microbial electrosynthesis. Biofilm formation could benefit both these applications, but was not yet reported for C. ljungdahlii.
Jo Philips +3 more
doaj +4 more sources
Elucidating the roles of essential genes in autotrophic metabolism and cell morphology of Clostridium ljungdahlii by CRISPRi [PDF]
Applied Microbiology and BiotechnologyUnderstanding the function of essential genes in Clostridium ljungdahlii is critical for unraveling its autotrophic metabolism and optimizing its potential as a platform for syngas fermentation.
Saira Munir +9 more
doaj +3 more sources
Development of a metabolic pathway transfer and genomic integration system for the syngas-fermenting bacterium Clostridium ljungdahlii [PDF]
Biotechnology for Biofuels, 2019 Background Clostridium spp. can synthesize valuable chemicals and fuels by utilizing diverse waste-stream substrates, including starchy biomass, lignocellulose, and industrial waste gases. However, metabolic engineering in Clostridium spp. is challenging
Gabriele Philipps +2 more
doaj +3 more sources
Metabolic Response of Clostridium ljungdahlii to Oxygen Exposure [PDF]
Appl Environ Microbiol, 2015 Clostridium ljungdahlii is an important synthesis gas fermenting bacterium used in the biofuels industry, and a preliminary investigation showed that it has some tolerance to oxygen when cultured in rich mixotrophic medium.
North Carolina State University (17855468)
core +5 more sources
A technique for lyopreservation of Clostridium ljungdahlii in a biocomposite matrix for CO absorption. [PDF]
PLoS ONE, 2017 A system capable of biocatalytic conversion of distributed sources of single carbon gases such as carbon monoxide into hydrocarbons can be highly beneficial for developing commercially viable biotechnology applications in alternative energy.
Mark J Schulte +8 more
doaj +5 more sources
Microbial Electrosynthesis Reshapes Energy Metabolism and Physiology in Clostridium ljungdahlii [PDF]
Microbial BiotechnologyMicrobial electrosynthesis (MES) enables a variety of microorganisms, particularly acetogens, to utilize electrical energy in the form of electrons to produce valuable compounds from CO2.
Sara Al Sbei +8 more
doaj +5 more sources
Characterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii [PDF]
Microb Cell Fact, 2013 Background The metabolic capabilities of acetogens to ferment a wide range of sugars, to grow autotrophically on H2/CO2, and more importantly on synthesis gas (H2/CO/CO2) make them very attractive candidates as production hosts for biofuels and ...
Zengler, Karsten +6 more
core +7 more sources
Growth and Product Formation of Clostridium ljungdahlii in Presence of Cyanide [PDF]
Frontiers in Microbiology, 2018 Cyanide is a minor constituent of crude syngas whose content depends on the feedstock and gasification procedure. It is a known poison to metal catalysts and inhibits iron-containing enzymes like carbon monoxide dehydrogenase of acetogenic organisms ...
Florian Oswald +4 more
doaj +6 more sources