Results 11 to 20 of about 1,705,145 (242)

Oxidatively generated complex DNA damage: Tandem and clustered lesions

open access: yes, 2012
There is an increasing interest for oxidatively generated complex lesions that are potentially more detrimental than single oxidized nucleobases. In this survey, the recently available information on the formation and processing of several classes of ...
Menoni, Hervé   +4 more
core   +9 more sources

Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome. [PDF]

open access: yesPLoS ONE, 2015
Clustered DNA damage is defined as multiple sites of DNA damage within one or two helical turns of the duplex DNA. This complex damage is often formed by exposure of the genome to ionizing radiation and is difficult to repair. The mutagenic potential and
Akira Sassa   +4 more
doaj   +1 more source

Understanding the multiple small magnitude induced seismic soil fatigue potential on hazard assessments

open access: yesCase Studies in Construction Materials, 2021
Soils under spacio-temporally clustered events loading are susceptible to soil fatigue as pore pressure dissipates and the soil is unable to recover. This potential for damage from soil fatigue is identified through an induced seismic fatigue equation ...
Merissa L. Zuzulock   +2 more
doaj   +1 more source

AUTOMATED BUILDING SEGMENTATION AND DAMAGE ASSESSMENT FROM SATELLITE IMAGES FOR DISASTER RELIEF [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2021
After a natural disaster or humanitarian crisis, rescue forces and relief organisations are dependent on fast, area-wide and accurate information on the damage caused to infrastructure and the situation on the ground. This study focuses on the assessment
X. Yuan   +10 more
doaj   +1 more source

Biochemical mechanisms and clusters of damage for high-let radiation [PDF]

open access: yesAdvances in Space Research, 1992
Using mechanisms of indirect and direct radiation, a generalized theory has been developed to account for strand break yields by high-LET particles. The major assumptions of this theory are: (i) damage at deoxyribose sites results primarily in strand break formation and (2) damage to bases leads to a variety of base alterations.
Chatterjee, A., Holley, W.R.
openaire   +3 more sources

The Influence of Single, Tandem, and Clustered DNA Damage on the Electronic Properties of the Double Helix: A Theoretical Study

open access: yesMolecules, 2020
Oxidatively generated damage to DNA frequently appears in the human genome as the effect of aerobic metabolism or as the result of exposure to exogenous oxidizing agents, such as ionization radiation.
Bolesław T. Karwowski
doaj   +1 more source

Ra-223 induces clustered DNA damage and inhibits cell survival in several prostate cancer cell lines

open access: yesTranslational Oncology, 2022
The bone-seeking radiopharmaceutical Xofigo (Radium-223 dichloride) has demonstrated both extended survival and palliative effects in treatment of bone metastases in prostate cancer.
Andris Abramenkovs   +4 more
doaj   +1 more source

Evaluasi Pengembangan Wilayah Permukiman Berdasarkan Pemetaan Kerusakan Permukiman Akibat Banjir Lahar Di Kali Putih, Kabupaten Magelang

open access: yesTataloka, 2013
The aim of this study are (1) to assess the damage of settlement due to lahar flood in study area, (2) to analyze the damage of settlement and (3) to analyze the allocated space of settlement development based on classification of damage settlement ...
Rosalina Kumalawati   +4 more
doaj   +1 more source

Assessing discriminative ability of risk models in clustered data. [PDF]

open access: yes, 2014
BACKGROUND: The discriminative ability of a risk model is often measured by Harrell's concordance-index (c-index). The c-index estimates for two randomly chosen subjects the probability that the model predicts a higher risk for the subject with poorer ...
van Klaveren, David   +13 more
core   +2 more sources

ZhimingZhou/Clustered-Embedding-Learning-for-Recommender-Systems: Release

open access: yes, 2023
Code for the paper 'Clustered Embedding Learning for Recommender Systems'
Zhiming Zhou
core   +1 more source

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