Results 11 to 20 of about 1,705,145 (242)
Oxidatively generated complex DNA damage: Tandem and clustered lesions
There is an increasing interest for oxidatively generated complex lesions that are potentially more detrimental than single oxidized nucleobases. In this survey, the recently available information on the formation and processing of several classes of ...
Menoni, Hervé +4 more
core +9 more sources
Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome. [PDF]
Clustered DNA damage is defined as multiple sites of DNA damage within one or two helical turns of the duplex DNA. This complex damage is often formed by exposure of the genome to ionizing radiation and is difficult to repair. The mutagenic potential and
Akira Sassa +4 more
doaj +1 more source
Soils under spacio-temporally clustered events loading are susceptible to soil fatigue as pore pressure dissipates and the soil is unable to recover. This potential for damage from soil fatigue is identified through an induced seismic fatigue equation ...
Merissa L. Zuzulock +2 more
doaj +1 more source
AUTOMATED BUILDING SEGMENTATION AND DAMAGE ASSESSMENT FROM SATELLITE IMAGES FOR DISASTER RELIEF [PDF]
After a natural disaster or humanitarian crisis, rescue forces and relief organisations are dependent on fast, area-wide and accurate information on the damage caused to infrastructure and the situation on the ground. This study focuses on the assessment
X. Yuan +10 more
doaj +1 more source
Biochemical mechanisms and clusters of damage for high-let radiation [PDF]
Using mechanisms of indirect and direct radiation, a generalized theory has been developed to account for strand break yields by high-LET particles. The major assumptions of this theory are: (i) damage at deoxyribose sites results primarily in strand break formation and (2) damage to bases leads to a variety of base alterations.
Chatterjee, A., Holley, W.R.
openaire +3 more sources
Oxidatively generated damage to DNA frequently appears in the human genome as the effect of aerobic metabolism or as the result of exposure to exogenous oxidizing agents, such as ionization radiation.
Bolesław T. Karwowski
doaj +1 more source
Ra-223 induces clustered DNA damage and inhibits cell survival in several prostate cancer cell lines
The bone-seeking radiopharmaceutical Xofigo (Radium-223 dichloride) has demonstrated both extended survival and palliative effects in treatment of bone metastases in prostate cancer.
Andris Abramenkovs +4 more
doaj +1 more source
The aim of this study are (1) to assess the damage of settlement due to lahar flood in study area, (2) to analyze the damage of settlement and (3) to analyze the allocated space of settlement development based on classification of damage settlement ...
Rosalina Kumalawati +4 more
doaj +1 more source
Assessing discriminative ability of risk models in clustered data. [PDF]
BACKGROUND: The discriminative ability of a risk model is often measured by Harrell's concordance-index (c-index). The c-index estimates for two randomly chosen subjects the probability that the model predicts a higher risk for the subject with poorer ...
van Klaveren, David +13 more
core +2 more sources
ZhimingZhou/Clustered-Embedding-Learning-for-Recommender-Systems: Release
Code for the paper 'Clustered Embedding Learning for Recommender Systems'
Zhiming Zhou
core +1 more source

