Results 31 to 40 of about 1,705,145 (242)

Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes. [PDF]

PLoS ONE, 2018
Due to its ability to induce DNA damage in a space and time controlled manner, ionising radiation is a unique tool for studying the mechanisms of DNA repair. The biological effectiveness of ionising radiation is related to the ionisation density which is
Lei Cheng, Beata Brzozowska, Alice Sollazzo, Lovisa Lundholm, Halina Lisowska, Siamak Haghdoost, Andrzej Wojcik   +6 more
doaj   +1 more source

The 2Ih and ^OXOG Proximity Consequences on Charge Transfer through ds-DNA: Theoretical Studies of Clustered DNA Damage

Molecules, 2023
Genetic information is continuously exposed to harmful factors, both intra- and extracellular. Their activity can lead to the formation of different types of DNA damage. Clustered lesions (CDL) are problematic for DNA repair systems.
Boleslaw T. Karwowski
doaj   +1 more source

Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's disease. [PDF]

PLoS ONE, 2012
Cells of the neural stem cell lineage in the adult subventricular zone (SVZ) respond to brain insult by increasing their numbers and migrating through the rostral migratory stream.
Xuefeng Jing, Hideto Miwa, Takahiro Sawada, Ichiro Nakanishi, Tomoyoshi Kondo, Masayasu Miyajima, Kazushige Sakaguchi   +6 more
doaj   +1 more source

Visualisation of γH2AX foci caused by heavy ion particle traversal; distinction between core track versus non-track damage.

PLoS ONE, 2013
Heavy particle irradiation produces complex DNA double strand breaks (DSBs) which can arise from primary ionisation events within the particle trajectory.
Nakako Izumi Nakajima, Holly Brunton, Ritsuko Watanabe, Amruta Shrikhande, Ryoichi Hirayama, Naruhiro Matsufuji, Akira Fujimori, Takeshi Murakami, Ryuichi Okayasu, Penny Jeggo, Atsushi Shibata   +10 more
doaj   +1 more source

Analisis Kerentanan Bahaya Gempa Bumi Tektonik Merusak Berdasarkan Fungsi Atenuasi Zhao Di Nusa Tenggara Timur

Indonesian Journal of Applied Physics, 2022
The East Nusa Tenggara (NTT) region which is located between 2 earthquakes, namely the tectonic plate subduction zone in the south and the Back Arc Thrust zone in the north, is very interesting to study considering the very active tectonic earthquakes ...
Irjan Irjan, ahmad luthfin, Septiana Nur Hidayati   +2 more
doaj   +1 more source

Supervised and non-supervised AE data classification of nanomodified CFRP during DCB tests [PDF]

FME Transactions, 2016
The aim of the paper is to use acoustic emissions to study the effect of electrospun nylon 6,6 Nanofibrous mat on carbon-epoxy composites during Double Cantilever beam (DCB) tests.
Fallahi N., Nardoni G., Heidary Hossein, Palazzetti R., Yan X.T., Zucchelli A.   +5 more
doaj  

Damage spreading in the random cluster model

Nuclear Physics B, 2022
8 pages, 17 ...
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

DNA Damage and Radical Reactions: Mechanistic Aspects, Formation in Cells and Repair Studies

CHIMIA, 2008
Several examples of oxidative and reductive reactions of DNA components that lead to single and tandem modifications are discussed in this review.
Jean Cadet, Thomas Carell, Luciano Cellai, Chryssostomos Chatgilialoglu, Thanasis Gimisis, Miguel Miranda, Peter O'Neill, Jean-Luc Ravanat, Marc Robert   +8 more
doaj   +1 more source

Automated Image Analysis of Transmission Electron Micrographs: Nanoscale Evaluation of Radiation-Induced DNA Damage in the Context of Chromatin

Cells, 2023
Background: Heavy ion irradiation (IR) with high-linear energy transfer (LET) is characterized by a unique depth dose distribution and increased biological effectiveness.
Mutaz A. Abd Al-razaq, Anna Isermann, Markus Hecht, Claudia E. Rübe   +3 more
doaj   +1 more source